Dr. Olga Gupta, M.D., received her undergraduate degree in Biomedical Engineering from Duke University, and her medical degree from the University of California San Francisco, followed by residency training in Pediatrics at Duke University, and a fellowship in Pediatric Endocrinology at the Children’s Hospital of Philadelphia. She joined the faculty of the University of Massachusetts Medical School in 2007 then moved to the University of Texas Southwestern in 2012. She was appointed the Medical Director of the pediatric Center for Obesity And Consequences of Health clinic in 2016. Under her leadership the COACH program is building an interdisciplinary team of pediatric subspecialists (endocrinology, cardiology, gastroenterology), nutritionists, physical therapists, social workers, behavioral psychologists and bariatric surgeons to create a comprehensive and productive environment to care for this vulnerable patient population.
The central goals of Dr. Gupta’s research are to better understand the psychosocial mechanisms leading to poor adherence to diabetes self-management tasks in young individuals with type 1 diabetes mellitus, and to develop novel behavioral interventions that are safe and effective for this population. Her recent publications on this topic revealed a clinically and statistically significant change in HbA1c at 3 months for the adolescent participants who received the intervention (a pet fish with instructions for pairing fish care with diabetes self-management tasks) compared with their peers in the control group (usual care). (Maranda et al., The Diabetes Educator, 2015). This work was featured on an NIH podcast and in the New York Times Well Section. She also demonstrated that youth who actively care for at least one household pet were 2.5 times more likely to have good glycemic control compared to children who didn’t care for a pet (Maranda and Gupta, PLoS ONE, 2016). Dr. Gupta has a firm commitment to serving pediatric patients with diabetes and through her research she strives to have a positive impact on the health of this population.
- Medical School
- University of California, San Francisco (2000)
- Duke University Medical Center (2003), Pediatrics
- Children's Hospital of Philadelphia (2006), Pediatric Endocrinology
- Graduate School
- University of Massachusetts Medical School (2010), Clinical Investigation
- Congenital hyperinsulinism
- Diabetes in adolescents
- Adipocyte-specific Hypoxia-inducible gene 2 promotes fat deposition and diet-induced insulin resistance.
- DiStefano MT, Roth Flach RJ, Senol-Cosar O, Danai LV, Virbasius JV, Nicoloro SM, Straubhaar J, Dagdeviren S, Wabitsch M, Gupta OT, Kim JK, Czech MP Mol Metab 2016 Dec 5 12 1149-1161
- Connexin 43 Mediates White Adipose Tissue Beiging by Facilitating the Propagation of Sympathetic Neuronal Signals.
- Zhu Y, Gao Y, Tao C, Shao M, Zhao S, Huang W, Yao T, Johnson JA, Liu T, Cypess AM, Gupta O, Holland WL, Gupta RK, Spray DC, Tanowitz HB, Cao L, Lynes MD, Tseng YH, Elmquist JK, Williams KW, Lin HV, Scherer PE Cell Metab. 2016 Sep 24 3 420-33
- Uric Acid, Parathyroid Hormone, and Vitamin D: New Players in an Old Game.
- Cartaya J, Gupta OT Metab Syndr Relat Disord 2016 Apr 14 3 135-6
- Association between Responsible Pet Ownership and Glycemic Control in Youths with Type 1 Diabetes.
- Maranda L, Gupta OT PLoS ONE 2016 11 4 e0152332
- Tenomodulin promotes human adipocyte differentiation and beneficial visceral adipose tissue expansion.
- Senol-Cosar O, Flach RJ, DiStefano M, Chawla A, Nicoloro S, Straubhaar J, Hardy OT, Noh HL, Kim JK, Wabitsch M, Scherer PE, Czech MP Nat Commun 2016 7 10686
- Visceral Adipose Tissue Mesothelial Cells: Living on the Edge or Just Taking Up Space?
- Gupta OT, Gupta RK Trends Endocrinol. Metab. 2015 Oct 26 10 515-23
- Activated Kupffer cells inhibit insulin sensitivity in obese mice.
- Tencerova M, Aouadi M, Vangala P, Nicoloro SM, Yawe JC, Cohen JL, Shen Y, Garcia-Menendez L, Pedersen DJ, Gallagher-Dorval K, Perugini RA, Gupta OT, Czech MP FASEB J. 2015 Mar
- Syndrome X (Metabolic Syndrome) for Generation Z! Why?
- Gupta OT Metab Syndr Relat Disord 2015 Feb
- A Novel Behavioral Intervention in Adolescents With Type 1 Diabetes Mellitus Improves Glycemic Control: Preliminary Results From a Pilot Randomized Control Trial.
- Maranda L, Lau M, Stewart SM, Gupta OT Diabetes Educ 2015 Jan
- Engaging Teens and Parents in Collaborative Practice: Perspectives on Diabetes Self-Management.
- Sullivan-Bolyai S, Bova C, Johnson K, Cullen K, Jaffarian C, Quinn D, Aroke EN, Crawford S, Lee MM, Gupta O Diabetes Educ 2014 Jan
Hypoglycemia. In Maternal, Fetal and Neonatal Physiology, S. Blackburn, ed.
Hardy O, Stanley C. (2012). Missouri, Elsevier
Premature Thelarche. In The 5-Minute Pediatric Consult, 4th Edition, M. Schwartz, L. Bell Jr, P. Bingham, E. Chung, D. Friedman, A. Mulberg, R. Tanel, eds.
Hardy O, Kelly A. (2005). Philadelphia, PA, Lippincott Williams & Wilkins.
Hyperinsulinism of Infancy: Localization of Focal Forms. In Pediatric PET Imaging, M. Charron, ed.
Hardy O, Stanley C. (2006). New York, Springer
Honors & Awards
- Leadership Emerging in Academic Departments
UT Southwestern Medical Center (2015)
- Dedman Family Scholar in Clinical Care
- Translational Medicine and Science Retreat
Poster Award (2010-2011)
- Best Paper Published from 2008's "Novel Insights from Clinical Practice"
Hormone Research (2009)
- Outstanding Patient-Oriented Research Poster
Institute for Diabetes, Obesity and Metabolism Spring Symposium and Kroc Lecture (2006)
- First Place Poster
National Cooperative Growth Study, Genentech (2005)
- Research Fellowship Grant
Lawson Wilkins Pediatric Endocrine Society (2005-2006)
- Behavioral Research in Diabetes Group Exchange (2013)
- American Association of Clinical Endocrinologists (2003-2006)
- American Diabetes Association (2003)
- Pediatric Endocrinology Society (2003)
- The Endocrine Society (2003)
- American Academy of Pediatrics (2000-2003)