The hypocholesterolemic agent LY295427 upregulates INSIG-1, identifying the INSIG-1 protein as a novel mediator of cholesterol homeostasis through SREBP.
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Structural requirements of ligands for the oxysterol receptors LXR alpha and beta
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Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear receptor LXR alpha.
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Identification of a signaling pathway mediated by the nuclear receptor, LXR alpha.
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Antisense transcripts are targets for activating small RNAs.
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Activating gene expression in mammalian cells with promoter-targeted duplex RNAs
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Involvement of AGO1 and AGO2 in mammalian transcriptional gene silencing
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Inhibiting transcription of chromosomal DNA with antigene peptide nucleic acids.
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Inhibiting gene expression at transcription start sites in chromosomal DNA with antigene RNAs.
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