Education

Undergraduate University of Rochester (2000), Chemistry
Graduate School Cornell University Medical College (2007), Molecular Cell Biology

Research Interest

  • host-pathogen interactions
  • innate immune response to viral infection
  • viral pathogenesis and host genetic determinants
  • virus reporters (fluorescent/luminescent) and screening technology

Publications

Featured Publications LegendFeatured Publications

Interferon-stimulated genes: roles in viral pathogenesis.
Schoggins JW Curr Opin Virol 2014 Apr 6C 40-46
Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity.
Schoggins JW, Macduff DA, Imanaka N, Gainey MD, Shrestha B, Eitson JL, Mar KB, Richardson RB, Ratushny AV, Litvak V, Dabelic R, Manicassamy B, Aitchison JD, Aderem A, Elliott RM, García-Sastre A, Racaniello V, Snijder EJ, Yokoyama WM, Diamond MS, Virgin HW, Rice CM Nature 2013 Nov
MX2 is an interferon-induced inhibitor of HIV-1 infection.
Kane M, Yadav SS, Bitzegeio J, Kutluay SB, Zang T, Wilson SJ, Schoggins JW, Rice CM, Yamashita M, Hatziioannou T, Bieniasz PD Nature 2013 Oct
Lipids in innate antiviral defense.
Schoggins JW, Randall G Cell Host Microbe 2013 Oct 14 4 379-85
IFNß-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damage.
Cheon H, Holvey-Bates EG, Schoggins JW, Forster S, Hertzog P, Imanaka N, Rice CM, Jackson MW, Junk DJ, Stark GR EMBO J. 2013 Sep
Innate immune responses to hepatitis C virus.
Schoggins JW, Rice CM Curr. Top. Microbiol. Immunol. 2013 369 219-42
Inhibition of HIV-1 particle assembly by 2',3'-cyclic-nucleotide 3'-phosphodiesterase.
Wilson SJ, Schoggins JW, Zang T, Kutluay SB, Jouvenet N, Alim MA, Bitzegeio J, Rice CM, Bieniasz PD Cell Host Microbe 2012 Oct 12 4 585-97
Mycobacterial disease and impaired IFN-? immunity in humans with inherited ISG15 deficiency.
Bogunovic D, Byun M, Durfee LA, Abhyankar A, Sanal O, Mansouri D, Salem S, Radovanovic I, Grant AV, Adimi P, Mansouri N, Okada S, Bryant VL, Kong XF, Kreins A, Velez MM, Boisson B, Khalilzadeh S, Ozcelik U, Darazam IA, Schoggins JW, Rice CM, Al-Muhsen S, Behr M, Vogt G, Puel A, Bustamante J, Gros P, Huibregtse JM, Abel L, Boisson-Dupuis S, Casanova JL Science 2012 Sep 337 6102 1684-8
Dengue reporter viruses reveal viral dynamics in interferon receptor-deficient mice and sensitivity to interferon effectors in vitro.
Schoggins JW, Dorner M, Feulner M, Imanaka N, Murphy MY, Ploss A, Rice CM Proc. Natl. Acad. Sci. U.S.A. 2012 Sep 109 36 14610-5
C7L family of poxvirus host range genes inhibits antiviral activities induced by type I interferons and interferon regulatory factor 1.
Meng X, Schoggins J, Rose L, Cao J, Ploss A, Rice CM, Xiang Y J. Virol. 2012 Apr 86 8 4538-47

Honors & Awards

  • Seymour and Vivian Milstein Young Investigator Award
    (2013)
  • NIH K01 Career Development Award
    (2012)
  • Sidney & Joan Pestka Award for Excellence in Interferon Research
    (2011)

Professional Associations/Affiliations

  • American Society of Microbiology (2014)
  • International Cytokine and Interferon Society (2011)
  • American Society of Virology (2009)