Dr. Ananth Madhuranthakam received his Ph.D. in Biomedical Engineering from Mayo Clinic, Rochester, MN, where his thesis work was focused on whole-body MR angiography under the supervision of Dr. Stephen Riederer. Upon graduation, he joined the MR Research and Development division of GE Healthcare to develop novel imaging techniques to improve the clinical utility of MRI. Subsequently, he joined UT Southwestern Medical Center in 2011 as an Assistant Professor in the Department of Radiology.
Dr. Madhuranthakam’s research interests focus on understanding and applying MR Physics to exploit the variations in human anatomy and physiology. The primary areas of research include non-contrast perfusion imaging using arterial spin labeling (ASL), structural and ventilation imaging of the lungs using ultra-short echo time (UTE), non-contrast MR angiography, and whole-body MRI techniques for cancer screening and staging.
A primary goal of their research is to develop a comprehensive non-contrast imaging approach to study the ventilation (V) and perfusion (Q) of the whole-lungs. To achieve this goal, his group is developing pulmonary perfusion imaging using ASL and pulmonary ventilation imaging using oxygen-enhanced UTE techniques. Such an approach will enable appropriate diagnosis and classification of patients with chronic lung disease such as COPD for monitoring disease progression and therapeutic response without exposure to ionizing radiation or exogenous contrast agents.
Dr. Madhuranthakam has 6 patents (4 issued and 2 filed), co-authored more than 20 peer-reviewed scientific journal papers and more than 70 conference proceedings. He serves as a scientific reviewer for various journals including Magnetic Resonance in Medicine (MRM) and Journal of Magnetic Resonance Imaging (JMRI).
- Anna University - India (2000)
- Graduate School
- Mayo Graduate School (2005), Biomedical Engineering
- Arterial Spin Labeling (ASL)
- Lung Perfusion and Ventilation (V/Q)
- Non-Contrast MR Angiography/Perfusion
- Whole Body Cancer Screening and Staging
- Arterial spin labeled perfusion imaging using three-dimensional turbo spin echo with a distributed spiral-in/out trajectory.
- Li Z, Schär M, Wang D, Zwart NR, Madhuranthakam AJ, Karis JP, Pipe JG Magn Reson Med 2015 Mar
- Improved short tau inversion recovery (iSTIR) for increased tumor conspicuity in the abdomen.
- Madhuranthakam AJ, Lee KS, Yassin A, Brittain JH, Pedrosa I, Rofsky NM, Alsop DC MAGMA 2013 Sep
- T(2)-weighted 3D fast spin echo imaging with water-fat separation in a single acquisition.
- Madhuranthakam AJ, Yu H, Shimakawa A, Busse RF, Smith MP, Reeder SB, Rofsky NM, Brittain JH, McKenzie CA J Magn Reson Imaging 2010 Sep 32 3 745-51
- Strategies for reducing respiratory motion artifacts in renal perfusion imaging with arterial spin labeling.
- Robson PM, Madhuranthakam AJ, Dai W, Pedrosa I, Rofsky NM, Alsop DC Magn Reson Med 2009 Jun 61 6 1374-87
- B1-insensitive fast spin echo using adiabatic square wave enabling of the echo train (SWEET) excitation.
- Madhuranthakam AJ, Busse RF, Brittain JH, Rofsky NM, Alsop DC Magn Reson Med 2008 Jun 59 6 1386-93
- Contrast-enhanced MR angiography of the peripheral vasculature with a continuously moving table and modified elliptical centric acquisition.
- Madhuranthakam AJ, Hu HH, Kruger DG, Glockner JF, Riederer SJ Radiology 2006 Jul 240 1 222-9
- Time-resolved 3D contrast-enhanced MRA of an extended FOV using continuous table motion.
- Madhuranthakam AJ, Kruger DG, Riederer SJ, Glockner JF, Hu HH Magn Reson Med 2004 Mar 51 3 568-76
- Technical Advancements in MR Neurography.
- Madhuranthakam AJ, Lenkinski RE Semin Musculoskelet Radiol 2015 Apr 19 2 86-93
- Added value of diffusion-weighted acquisitions in MRI of the abdomen and pelvis.
- Moore WA, Khatri G, Madhuranthakam AJ, Sims RD, Pedrosa I AJR Am J Roentgenol 2014 May 202 5 995-1006
- Ultrashort echo time MRI of pulmonary water content: assessment in a sponge phantom at 1.5 and 3.0 Tesla.
- Molinari F, Madhuranthakam AJ, Lenkinski R, Bankier AA Diagn Interv Radiol 2014 Jan-Feb 20 1 34-41
Honors & Awards
- Distinguished Reviewer
Journal of Magnetic Resonance Imaging (2014-2015)
- Distinguished Reviewer
Magnetic Resonance in Medicine (2012-2015)
- ISMRM Travel Award
Presentation at annual scientific meetings in Toronto (2003), Kyoto (2004) and Miami (2005) (2003-2005)
- Jawaharlal Nehru Center for Advanced Scientific Research Fellowship
Summer Undergraduate Research Fellowship (SURF) (1999)
- American Heart Association (2013)
- International Society for Magnetic Resonance in Medicine (ISMRM) (2001)