Education

Undergraduate
Hokkaido University - Japan (1998)
Graduate School
Hokkaido University - Japan (2000), Chemistry
Graduate School
Hokkaido University - Japan (2003), Chemistry

Publications

Featured Publications LegendFeatured Publications

Rationale and evidence to combine radiation therapy and immunotherapy for cancer treatment.
Ishihara D, Pop L, Takeshima T, Iyengar P, Hannan R Cancer Immunol. Immunother. 2016 Oct
Real-time 4-D radiotherapy for lung cancer.
Shirato H, Onimaru R, Ishikawa M, Kaneko J, Takeshima T, Mochizuki K, Shimizu S, Umegaki K Cancer Sci. 2012 Jan 103 1 1-6
Radiation-induced cancer cell repopulation: a possible mechanism implied by experiments using transplantable mouse-derived sarcoma cell line.
Nishioka T, Yasuda M, Takeshima T, Haga H, Miyai Y, Shibata K, Yamazaki R, Shirato H, Teduka M, Date H Cell Struct. Funct. 2011 36 1 13-20
Combination immunotherapy with radiation and CpG-based tumor vaccination for the eradication of radio- and immuno-resistant lung carcinoma cells.
Chamoto K, Takeshima T, Wakita D, Ohkuri T, Ashino S, Omatsu T, Shirato H, Kitamura H, Togashi Y, Nishimura T Cancer Sci. 2009 May 100 5 934-9
Combination tumor immunotherapy with radiotherapy and Th1 cell therapy against murine lung carcinoma.
Yokouchi H, Chamoto K, Wakita D, Yamazaki K, Shirato H, Takeshima T, Dosaka-Akita H, Nishimura M, Yue Z, Kitamura H, Nishimura T Clin. Exp. Metastasis 2007 24 7 533-40
Liposome-encapsulated CpG oligodeoxynucleotides as a potent adjuvant for inducing type 1 innate immunity.
Suzuki Y, Wakita D, Chamoto K, Narita Y, Tsuji T, Takeshima T, Gyobu H, Kawarada Y, Kondo S, Akira S, Katoh H, Ikeda H, Nishimura T Cancer Res. 2004 Dec 64 23 8754-60
STAT6-mediated signaling in Th2-dependent allergic asthma: critical role for the development of eosinophilia, airway hyper-responsiveness and mucus hypersecretion, distinct from its role in Th2 differentiation.
Hoshino A, Tsuji T, Matsuzaki J, Jinushi T, Ashino S, Teramura T, Chamoto K, Tanaka Y, Asakura Y, Sakurai T, Mita Y, Takaoka A, Nakaike S, Takeshima T, Ikeda H, Nishimura T Int. Immunol. 2004 Oct 16 10 1497-505
The critical role of type-1 innate and acquired immunity in tumor immunotherapy.
Ikeda H, Chamoto K, Tsuji T, Suzuki Y, Wakita D, Takeshima T, Nishimura T Cancer Sci. 2004 Sep 95 9 697-703