Ruth Gordillo, Ph.D.

Ruth Gordillo, Ph.D., is an Associate Professor in the Department of Internal Medicine and the Director of the UT Southwestern Metabolic Phenotyping Core. She is a member of the faculty in the Touchstone Diabetes Center.

Originally from Badajoz, Spain, Dr. Gordillo holds a bachelor's degree and master's degree in chemistry, as well as her doctorate in science and chemistry, from the Universidad de Extremadura in Spain. She completed postdoctoral fellowships in organic chemistry at Universidad de Extremadura and physical organic chemistry and computational chemistry at the University of California Los Angeles.

Dr. Gordillo joined the UT Southwestern faculty in 2015.

She specializes in the development of LC/MS/MS technologies for the determination and quantification of metabolites.

Undergraduate

Universidad De Extremadura (1997), Chemistry

Graduate School

Universidad De Extremadura (1998), Chemistry

Graduate School

Universidad De Extremadura (2002), Science

• Lipidomics
• Mass Spectrometry
• Metabolomics
• Pharmacodynamics
• Pharmacokinetics

Featured Publications

An Endothelial-to-Adipocyte Extracellular Vesicle Axis Governed by Metabolic State.

Crewe C, Joffin N, Rutkowski JM, Kim M, Zhang F, Towler DA, Gordillo R, Scherer PE Cell 2018 Oct 175 3 695-708.e13

Specific Hepatic Sphingolipids Relate to Insulin Resistance, Oxidative Stress, and Inflammation in Nonalcoholic Steatohepatitis.

Apostolopoulou M, Gordillo R, Koliaki C, Gancheva S, Jelenik T, De Filippo E, Herder C, Markgraf D, Jankowiak F, Esposito I, Schlensak M, Scherer PE, Roden M Diabetes Care 2018 Mar

Adipocyte Xbp1s overexpression drives uridine production and reduces obesity.

Deng Y, Wang ZV, Gordillo R, Zhu Y, Ali A, Zhang C, Wang X, Shao M, Zhang Z, Iyengar P, Gupta RK, Horton JD, Hill JA, Scherer PE Mol Metab 2018 Mar

Acute loss of adipose tissue-derived adiponectin triggers immediate metabolic deterioration in mice.

Xia JY, Sun K, Hepler C, Ghaben AL, Gupta RK, An YA, Holland WL, Morley TS, Adams AC, Gordillo R, Kusminski CM, Scherer PE Diabetologia 2017 Dec

An adipo-biliary-uridine axis that regulates energy homeostasis.

Deng Y, Wang ZV, Gordillo R, An Y, Zhang C, Liang Q, Yoshino J, Cautivo KM, De Brabander J, Elmquist JK, Horton JD, Hill JA, Klein S, Scherer PE Science 2017 Mar 355 6330

Plasma ceramides are elevated in female children and adolescents with type 2 diabetes.

Lopez X, Goldfine AB, Holland WL, Gordillo R, Scherer PE J. Pediatr. Endocrinol. Metab. 2013 Apr 1-4

• Outstanding Thesis Award
  University of Extremadura (Spain) (2002)
• Postdoctoral Fellowship
  University of Extremadura (Spain) (2002)
• Postdoctoral Fellowship
  Government of Spain (2002)
• Predoctoral Scholarship
  Government of Spain (1998)
• Visitor Research Scholarship
  Government of Spain (1998)

• American Chemical Society (2003)
• American Society for Mass Spectrometry (2005)
• Sociedad Española de Espectrometría de Masas (2013)