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Robert Hammer, Ph.D.

Robert Hammer, Ph.D.

Professor

Endowed Title
Graydon Heartsill Professorship in Medical Science
School
Medical School
Department
Biochemistry
Graduate Programs
Cancer Biology, Genetics, Development and Disease
  • Education
    Undergraduate
    Kalamazoo College , Biology
    Graduate School
    Wayne State University (1981)
  • Research Interest
    • Genome editing and transgenesis
    • Oncogene and nutrient collaboration in cancer
    • Ribosomopathies
    • Rodent models of cancer
  • Publications

    Star Featured Publications

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    Hepatoblastoma modeling in mice places nrf2 within a cancer field established by mutant ?-catenin.
    Comerford SA, Hinnant EA, Chen Y, Bansal H, Klapproth S, Rakheja D, Finegold MJ, Lopez-Terrada D, O?Donnell KA, Tomlinson GE, Hammer RE. J Clin Invest Insight. 2016 16 e88549.
    Acetate dependence of tumors.
    Comerford SA, Huang Z, Du X, Wang Y, Cai L, Witkiewicz A, Walters H, Tantawy MN, Fu A, Manning C, Horton JD, Hammer RE, McKnight SL, Tu BP Cell. 2014 159 1591-1602
    Comparative analysis of SV40 17kT and LT function in vivo demonstrates that LT's C-terminus re-programs hepatic gene expression and is necessary for tumorigenesis in the liver.
    Comerford SA, Schultz N, Hinnant EA, Klapproth S, Hammer RE Oncogenesis 2012 1 e28
    Induction of hepatocyte proliferation and death by modulation of T-Antigen expression.
    Comerford, S.A., Clouthier, D.E., Hinnant, E., and Hammer, R.E. Oncogene 2003 22 2515-2530
  • Honors & Awards
    • State Capital of Wiesbaden, Germany
      Carol-Nachman Prize in Rheumatology (1992)
    • USDA Unit Award for Distinguished Service
      Application of Gene Transfer to Farm Animals (1989)
    • University of Pennsylvania School of Veterinary Medicine
      NIH Postdoctoral Fellowship (1983)
  • Professional Associations/Affiliations
    • International Society for Stem Cell Research (ISSCR) (2018)
    • International Society of Transgenic Technology (ISTT) (2010)
    • Public Responsibility in Medicine and Research (PRIMR) (2016)
    • Society for Developmental Biology (2020)