Zhong-Jian Shen, M.D., Ph.D.

Instructor

School: Medical School
Department: Pathology

Education

Graduate School: Kyungpook National University (1999), Biochemistry

Publications

Featured Publications

Pin1 protein regulates Smad protein signaling and pulmonary fibrosis.: Shen ZJ, Braun RK, Hu J, Xie Q, Chu H, Love RB, Stodola LA, Rosenthal LA, Szakaly RJ, Sorkness RL, Malter JS J. Biol. Chem. 2012 Jul 287 28 23294-305
The peptidyl-prolyl isomerase Pin1 facilitates cytokine-induced survival of eosinophils by suppressing Bax activation.: Shen ZJ, Esnault S, Schinzel A, Borner C, Malter JS Nat. Immunol. 2009 Mar 10 3
Thymic stromal lymphopoietin expression in allergic pulmonary inflammation is Pin1-dependent.: Esnault S, Rosenthal LA, Shen ZJ, Westmark CJ, Sorkness RL, Malter JS J. Allergy Clin. Immunol. 2008 May 121 5
Pin1 regulates TGF-beta1 production by activated human and murine eosinophils and contributes to allergic lung fibrosis.: Shen ZJ, Esnault S, Rosenthal LA, Szakaly RJ, Sorkness RL, Westmark PR, Sandor M, Malter JS J. Clin. Invest. 2008 Feb 118 2 479-90
Pinning down signaling in the immune system: the role of the peptidyl-prolyl isomerase Pin1 in immune cell function.: Esnault S, Shen ZJ, Malter JS Crit. Rev. Immunol. 2008 28 1
A critical role for Pin1 in allergic pulmonary eosinophilia in rats.: Esnault S, Rosenthal LA, Shen ZJ, Sedgwick JB, Szakaly RJ, Sorkness RL, Malter JS J. Allergy Clin. Immunol. 2007 Nov 120 5
Antisense targeting of TGF-beta1 augments BMP-induced upregulation of osteopontin, type I collagen and Cbfa1 in human Saos-2 cells.: Shen ZJ, Kim SK, Jun DY, Park W, Kim YH, Malter JS, Moon BJ Exp. Cell Res. 2007 Apr 313 7
Pin1 modulates the type 1 immune response.: Esnault S, Braun RK, Shen ZJ, Xiang Z, Heninger E, Love RB, Sandor M, Malter JS PLoS ONE 2007 2 2
The peptidyl-prolyl isomerase Pin1 regulates granulocyte-macrophage colony-stimulating factor mRNA stability in T lymphocytes.: Esnault S, Shen ZJ, Whitesel E, Malter JS J. Immunol. 2006 Nov 177 10
The peptidyl-prolyl isomerase Pin1 regulates the stability of granulocyte-macrophage colony-stimulating factor mRNA in activated eosinophils.: Shen ZJ, Esnault S, Malter JS Nat. Immunol. 2005 Dec 6 12 1280-7