Featured Publications
Formation and Fate of a Complete 31-Protein RNA Polymerase II Transcription Preinitiation Complex.
Murakami K, Calero G, Brown CR, Liu X, Davis RE, Boeger H, Kornberg RD J. Biol. Chem. 2013 Mar 288 9 6325-32
RNA polymerase II transcription: Structure and mechanism.
Liu X, Bushnell DA, Kornberg RD Biochim. Biophys. Acta 2012 Sep
Tfb6, a previously unidentified subunit of the general transcription factor TFIIH, facilitates dissociation of Ssl2 helicase after transcription initiation.
Murakami K, Gibbons BJ, Davis RE, Nagai S, Liu X, Robinson PJ, Wu T, Kaplan CD, Kornberg RD Proc. Natl. Acad. Sci. U.S.A. 2012 Mar 109 13 4816-21
Lock and Key to Transcription: s-DNA Interaction.
Liu X, Bushnell DA, Kornberg RD Cell 2011 Dec 147 6 1218-9
Initiation complex structure and promoter proofreading.
Liu X, Bushnell DA, Silva DA, Huang X, Kornberg RD Science 2011 Jul 333 6042 633-7
Structure of an RNA polymerase II-TFIIB complex and the transcription initiation mechanism.
Liu X, Bushnell DA, Wang D, Calero G, Kornberg RD Science 2010 Jan 327 5962 206-9
The structural basis of protein acetylation by the p300/CBP transcriptional coactivator.
Liu X, Wang L, Zhao K, Thompson PR, Hwang Y, Marmorstein R, Cole PA Nature 2008 Feb 451 7180 846-50
Structure of the retinoblastoma protein bound to adenovirus E1A reveals the molecular basis for viral oncoprotein inactivation of a tumor suppressor.
Liu X, Marmorstein R Genes Dev. 2007 Nov 21 21 2711-6
Molecular basis for bre5 cofactor recognition by the ubp3 deubiquitylating enzyme.
Li K, Ossareh-Nazari B, Liu X, Dargemont C, Marmorstein R J. Mol. Biol. 2007 Sep 372 1 194-204
Multiple roles for acetylation in the interaction of p300 HAT with ATF-2.
Karanam B, Wang L, Wang D, Liu X, Marmorstein R, Cotter R, Cole PA Biochemistry 2007 Jul 46 28 8207-16
