Download Curriculum Vitae


 2005 Purdue University. PhD, Bioanalytical Chemistry. Advisor: Fred E. Regnier

2001 Ball State University. MS, Synthetic Organic Chemistry. Advisor: Mohammad Behforouz



 2005-2006 Purdue University, Advisor: Fred E. Regnier

 2006-2011 Institute for Systems Biology, Advisor: Ruedi Aebersold



2011-present Assistant Professor , Department of Biochemistry, UT Southwestern


Isfahan University - Iran (1999), Chemistry
Graduate School
Ball State University (2001), Chemistry
Graduate School
Purdue University Main Campus (2005), Chemistry

Research Interest

  • Aging
  • Drug discovery
  • Neurodegeneration
  • Proteomics


Featured Publications LegendFeatured Publications

Marker for type VI secretion system effectors.
Salomon D, Kinch LN, Trudgian DC, Guo X, Klimko JA, Grishin NV, Mirzaei H, Orth K Proc. Natl. Acad. Sci. U.S.A. 2014 Jun 111 25 9271-6
GOAT - A simple LC-MS/MS gradient optimization tool.
Trudgian DC, Fischer R, Guo X, Kessler BM, Mirzaei H Proteomics 2014 Apr
Phosphorylation-Regulated Binding of RNA Polymerase II to Fibrous Polymers of Low-Complexity Domains.
Kwon I, Kato M, Xiang S, Wu L, Theodoropoulos P, Mirzaei H, Han T, Xie S, Corden JL, McKnight SL Cell 2013 Nov 155 5 1049-60
A Gain-of-Function Mutation in DHT Synthesis in Castration-Resistant Prostate Cancer.
Chang KH, Li R, Kuri B, Lotan Y, Roehrborn CG, Liu J, Vessella R, Nelson PS, Kapur P, Guo X, Mirzaei H, Auchus RJ, Sharifi N Cell 2013 Aug 154 5 1074-84
Sulfur Amino Acids Regulate Translational Capacity and Metabolic Homeostasis through Modulation of tRNA Thiolation.
Laxman S, Sutter BM, Wu X, Kumar S, Guo X, Trudgian DC, Mirzaei H, Tu BP Cell 2013 Jul 154 2 416-29
Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1.
Sun Q, Carrasco YP, Hu Y, Guo X, Mirzaei H, Macmillan J, Chook YM Proc. Natl. Acad. Sci. U.S.A. 2013 Jan 110 4 1303-8
Cloud CPFP: a shotgun proteomics data analysis pipeline using cloud and high performance computing.
Trudgian DC, Mirzaei H J. Proteome Res. 2012 Dec 11 12 6282-90

Honors & Awards

  • Missing Links Award
    Cancer Prevention Research Institute of Texas (2011)
  • Top 10 most cited author of the year
    ACS (2006)
  • Dean’s Citation for Academic Excellence
    Ball State University (2001)
  • Outstanding Chemistry Graduate Student and Graduate Teaching Award
    Ball State University (2001)