Education

Undergraduate Cornell University (1996), Biology
Medical School Johns Hopkins University (2004), Medicine
Graduate School Johns Hopkins University (2004), Molecular Biology

Research Interest

  • Cancer
  • MicroRNAs
  • Noncoding RNAs
  • Post-transcriptional Regulation

Publications

Featured Publications LegendFeatured Publications

Repression of the miR-143/145 cluster by oncogenic Ras initiates a tumor-promoting feed-forward pathway

Kent OA, Chivukula RR, Mullendore M, Wentzel EA, Feldmann G, Lee KH, Liu S, Leach SD, Maitra A, and Mendell JT Genes and Development December 2010 24 (24) 2754-2759

Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation

Chang TC, Zeitels LR, Hwang HW, Chivukula RR, Wentzel EA, Dews M, Jung J, Gao P, Dang CV, Beer MA, Thomas-Tikhonenko A, Mendell JT PNAS 2009 106 (9) 3384-9

Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model

Kota J, Chivukula RR, O?Donnell KA, Wentzel EA, Montgomery CL, Hwang HW, Chang TC, Clark KR, Mendell JR, Mendell JT Cell 2009 137 (6) 1005-1017

Cell-cell contact globally activates microRNA biogenesis

Hwang HW, Wentzel EA, Mendell JT PNAS 2009 106 (17) 7016-7021

c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism

Gao P, Tchernyshyov I, Chang TC, Lee YS, Kita K, Ochi T, Zeller KI, De Marzo AM, Van Eyk JE, Mendell JT, Dang CV Nature 2009 458 (7239) 762-5

Honors & Awards

  • CPRIT Scholar in Cancer Research
    (2011)
  • AACR Outstanding Achievement in Cancer Research Award
    (2010)
  • Howard Hughes Medical Institute Early Career Scientist
    (2009)
  • Allan C. Davis Medal
    Outstanding Young Scientist in the State of Maryland (2007)
  • Rita Allen Foundation Scholar
    (2006)