Featured Publications
miRiad roles for the miR-17-92 cluster in development and disease
Mendell JT Cell 2008 133 (2) 217-222
Widespread microRNA repression by Myc contributes to tumorigenesis
Chang TC, Yu D, Lee YS, Wentzel EA, Arking DE, West KM, Dang CV, Thomas-Tikhonenko A, Mendell JT Nature Genetics 2008 40 43-50
Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis
Chang TC, Wentzel EA, Kent OA, Ramachandran K, Mullendore M, Lee KH, Feldmann G, Yamakuchi M, Ferlito M, Lowenstein CJ, Arking DE, Beer MA, Maitra A, Mendell JT Molecular Cell 2007 26 745-752
A Hexanucleotide element directs microRNA nuclear import
Hwang HW, Wentzel EA, Mendell JT Science 2007 315 97-100
c-Myc-regulated microRNAs modulate E2F1 expression
O’Donnell KA, Wentzel EA, Zeller KI, Dang CV, and Mendell JT Nature 2005 435 (7043) 839-843
Repression of the miR-143/145 cluster by oncogenic Ras initiates a tumor-promoting feed-forward pathway
Kent OA, Chivukula RR, Mullendore M, Wentzel EA, Feldmann G, Lee KH, Liu S, Leach SD, Maitra A, and Mendell JT Genes and Development December 2010 24 (24) 2754-2759
Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation
Chang TC, Zeitels LR, Hwang HW, Chivukula RR, Wentzel EA, Dews M, Jung J, Gao P, Dang CV, Beer MA, Thomas-Tikhonenko A, Mendell JT PNAS 2009 106 (9) 3384-9
Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model
Kota J, Chivukula RR, O?Donnell KA, Wentzel EA, Montgomery CL, Hwang HW, Chang TC, Clark KR, Mendell JR, Mendell JT Cell 2009 137 (6) 1005-1017
Cell-cell contact globally activates microRNA biogenesis
Hwang HW, Wentzel EA, Mendell JT PNAS 2009 106 (17) 7016-7021
c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism
Gao P, Tchernyshyov I, Chang TC, Lee YS, Kita K, Ochi T, Zeller KI, De Marzo AM, Van Eyk JE, Mendell JT, Dang CV Nature 2009 458 (7239) 762-5
