Dwight German, Ph.D.

Undergraduate	Southern Methodist University (1966)
Graduate School	University of Oklahoma Norman Campus (1967)
Graduate School	University of Oklahoma Health Sciences Center (1972)

• Human post-mortem tissue and animal models of both Parkinsons disease and Alzheimers disease are studied to understand the mechanisms responsible for selective vulnerability of specific populations of neurons. The animal models are also used to study potential therapies.
• My lab focuses on the cellular and molecular mechanisms responsible for neurodegenerative and psychiatric diseases.
• Post-mortem tissues from individuals with affective disorder are used to identify cellular and molecular alterations to provide insight into the etiology of the disorders.

Featured Publications

Identification of candidate IgG biomarkers for Alzheimer?s disease via combinatorial library screening.

Reddy MM, Wilson R, Wilson J, Connell S, Gocke A, Hynan L, German D, Kodadek T. Cell 2011 144 132-142

Elevated pesticide levels in the serum are associated with increased risk for Parkinsons disease.

Richardson, J.R., Shalat, S.L., Buckley, B., Winnik, B., OSuilleabhain, P., Diaz-Arrastia, R., Reisch, J., German, D.C. Arch. Neurol. 2009 66 (7) 870-875

Stereotaxic near-infrared probe for localization during functional neurosurgical procedures: further experience.

Giller, C.A., Liu, H., German, D.C., Dewey, R.B. J. Neurosurgery 2009 110 263-273

Chronic intraventricular administration of 1-methyl-4-phenylpyridinium as a progressive model of Parkinsons disease.

Sonsalla, P.K., Zeevalk, G., German, D.C. Parkinsonism & Related Disorders 2008 14 Suppl 2 116-118

Mouse models of Alzheimers disease.

D.C. German In - A-beta peptide and Alzheimers disease. C. J. Barrow and D. H. Small, eds. Springer Verlag, London. 2007 Chapter 16 259-273

Serum biomarkers for Alzheimers disease: proteomic discovery.

German DC, Gurnani P, Nandi A, Garner HR, Fisher W, Diaz-Arrastia R, O’Suilleabhain P, Rosenblatt KP. Biomedicine & Pharmacotherapy 2007 61 383-389

• Grant Review Committee, Michael J. Fox Foundation
  (2010)
• Nominator for Kyoto Prize
  (2010)
• Grant Review Committee, Alzheimers Association
  (2009)
• Editorial Board, Current Molecular Pharmacology
  (2008)

• American Association for the Advancement of Science
• Society for Neuroscience