Dwight German, Ph.D.

Professor

Department: Psychiatry

Graduate Programs: Clinical Psychology, Integrative Biology

Education

Undergraduate Southern Methodist University (1966)
Graduate School University of Oklahoma Norman Campus (1967)
Graduate School University of Oklahoma Health Sciences Center (1972)

Research Interests

  • Blood biomarkers are being sought for Parkinson?s disease, Alzheimer?s disease and autism. Blood samples from patients with these diseases are analyzed to identify potential antibody and protein biomarkers that can be used to diagnose the diseases, and possibly identify the diseases before symptoms occur.
  • Environmental links to neurodegenerative disease: role of pesticides. Pesticide exposure (e.g., Lindane and DDT) may be responsible for some cases of Parkinson?s disease and Alzheimer?s disease.
  • Parkinson's disease and Alzheimer's disease are studied to understand the mechanisms responsible for neurodegeneration. Blood and brain tissue from patients and animal models of these diseases are used.

Publications

Featured Publications Legend

Featured Publications

Validation of a serum screen for Alzheimer's disease across assay platforms, species and tissue.

O'Bryant SE, Xiao G, Zhang F, Edwards ML, German DC, Yin X, Como T, Reisch J, Huebinger HM, Graff-Radford N, Dickson D, Barber RC, Hall J, O?Suilleabhain P, Grammas P. 2014

Neuropathology and animal models of autism: genetic and environmental factors.

Gadad BS, Hewitson L, Young KA, German DC. 2013

Apoptosis signal-regulating kinase 1 mediates MPTP toxicity and regulates glial activation.

Lee K-W, Zhao X, Im J-Y, Grosso H, Jang WH, Chan TW, Sonsalla PK, German DC, Ichijo H, Junn E, Mouradian MM. 2012

Beta-hexachlorocyclohexane levels in serum and risk of Parkinson's disease.

Richardson JR, Roy A, Shalat SL, Buckley B, Winnik B, Gearing M, Levey AI, Factor SA, O?Suilleabhain P, German DC. 2011

Stereotaxic near-infrared probe for localization during functional neurosurgical procedures: further experience.

Giller, C.A., Liu, H., German, D.C., Dewey, R.B. J. Neurosurgery 2009 110 263-273

Chronic intraventricular administration of 1-methyl-4-phenylpyridinium as a progressive model of Parkinsons disease.

Sonsalla, P.K., Zeevalk, G., German, D.C. Parkinsonism & Related Disorders 2008 14 Suppl 2 116-118

Mouse models of Alzheimers disease.

D.C. German In - A-beta peptide and Alzheimers disease. C. J. Barrow and D. H. Small, eds. Springer Verlag, London. 2007 Chapter 16 259-273

Serum biomarkers for Alzheimers disease: proteomic discovery.

German DC, Gurnani P, Nandi A, Garner HR, Fisher W, Diaz-Arrastia R, O’Suilleabhain P, Rosenblatt KP. Biomedicine & Pharmacotherapy 2007 61 383-389

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Honors/Awards

  • Grant Reviewer for New Jersey Governor’s Council for Medical Research and Treatment of Autism
    (2013)
  • Nominator for Kyoto Prize
    (2010)
  • Grant Review Committee, Alzheimers Association
    (2009)
  • Editorial Board, Current Molecular Pharmacology
    (2008)

Professional Associations/Affiliations

  • American Association for the Advancement of Science
  • Society for Neuroscience