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My primary research interests are in sensorimotor and brain development in autism spectrum and related neurodevelopmental disorders (e.g., Phelan-McDermid Syndrome, or PMS; Fragile X Syndrome). We also currently conduct studies on neurodegenerative disorders characterized by deterioration of sensorimotor skills, such as Fragile X-associated tremor/ataxia syndrome (FXTAS). All of our studies integrate systems neuroscience approaches including functional MRI, diffusion tensor imaging (DTI), electromyography (EMG), kinematic and kinetic analysis and oculomotor recording. Ongoing studies of autism aim to identify new biomarkers that may help resolve heterogeneity and be used to establish initial diagnoses more reliably and earlier in development. Broadly speaking, our research on sensorimotor and brain development aims to characterize pathophysiological mechanisms in disorders of brain development, and determine new targets for drug development. 

I earned my masters and PhD in Child Clinical Psychology from the University of North Carolina at Chapel Hill and then completed a postdoctoral fellowship in cognitive neuroscience and neuroimaging at the University of Illinois at Chicago. I am currently an Assistant Professor in Psychiatry and Pediatrics and an investigator in the new Center for Autism and Developmental Disabilities (CADD).


University of North Carolina at Chapel Hill
Undergraduate School
Emory University (1999)
Graduate School
University of North Carolina at Chapel Hill (2006)
UT Southwestern Medical Center (2009)

Research Interest

  • Autism
  • FMR1 disorders, inculding Fragile X Syndrome and Fragile X-associated tremor/ataxia syndrome (FXTAS)
  • Intermediate phenotypes in psychiatric research
  • Phelan-McDermid Syndrome
  • Sensorimotor development


Featured Publications LegendFeatured Publications

Motor dysfunction as a core trait in autism spectrum disorders.
Mosconi MW & Sweeney JA Science China: Life Sciences In Press
Motor impairments and dyspraxia in autism.
Mosconi MW, Takarae Y, & Sweeney JA Autism Spectrum Disorders. Oxford University Press. 2012
Resting state EEG abnormalities in autism spectrum disorders
Wang J, Barstein J, Ethridge L, Mosconi MW, Takarae Y, Sweeney JA Journal of Neurodevelopmental Disorders 2013 1 5
Reduced behavioral flexibility in autism spectrum disorders is related to insistence on sameness
DCruz AM, Ragozzino ME, Mosconi MW, Cook EH, & Sweeney JA Neuropsychology 2013 2 27 152-160
Rare inherited A2BP1 deletion in a proband with autism and developmental hemiparesis
Davis LK, Maltman N, Mosconi MW, Macmillan C, Schmitt L, Francis SM, Jacob S, Sweeney JA, & Cook EH American Journal of Medical Genetics 2012 7 158A 1654-1661

Honors & Awards

  • International Society for Autism Research (INSAR) Young Investigator Award
    Award given to promising young investigators in autism research (2014)
  • Motor Control and Cerebellar Mechanisms in Fragile X-Associated Tremor Ataxia Syndrome (FXTAS)
    Once Upon A Time Foundation Award (2013-2015)
  • NIH/NIMH K23 Career Development Award
  • Autism Speaks Research Fellowship
  • Society for Neural Control of Movement Conference Scholarship
  • International Society for Autism Research Dissertation Award
  • NIH Postdoctoral Training Fellowship Award