Dr. James Kim received his MD and PhD degrees from the University of Rochester, where he also completed his Internal Medicine Residency. Dr. Kim completed a medical oncology fellowship at the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. During his fellowship, Dr. Kim joined the laboratory of Dr. Philip Beachy (at both Johns Hopkins and Stanford University) where he studied the role of Hedgehog signaling pathway, a critical developmental pathway, in cancer and small molecule inhibitors of this pathway.

At UT Southwestern, Dr. Kim’s laboratory focuses on how fundamental developmental pathways, such as Hedgehog, are involved in the initiation, growth, and metastases of cancers through the use of cancer mouse models and cell and molecular biological techniques. The laboratory also seeks to understand interactions of these pathways with each other and between tumor epithelia and stroma. In his clinic, Dr. Kim specializes in the care of patients with lung cancer and other thoracic malignancies.


Undergraduate Amherst College (1990), Chemistry
Graduate School University of Rochester (1997), Chemistry
Medical School University of Rochester (1999), Medicine

Research Interest

  • Developmental Pathways
  • Hedgehog Signaling Pathway
  • Lung Cancer
  • Molecularly Targeted Therapy
  • Tumor Epithelial-Stromal Interactions


Featured Publications LegendFeatured Publications

Honors & Awards

  • Simmons Cancer Center and American Cancer Society New Investigator Award
  • National Lung Cancer Partnership Young Investigator Research Grant
  • American Society of Clinical Oncology Young Investigator Award

Professional Associations/Affiliations

  • American Association for Cancer Research (2003)
  • American Society of Clinical Oncology (2002)