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Dr. Frohman is currently Professor, with Tenure, of Neurology and Neurotherapeutics, and Ophthalmology, holder of the Kenney Marie Dixon-Pickens Distinguished Professorship in Multiple Sclerosis Research, holder of the Cain Denius Endowment for MS Research, and the Irene Wadel and Robert Atha Distinguished Chair in Neurology, and Director of the Multiple Sclerosis Program in the Department of Neurology and Neurotherapeutics at the University of Texas Southwestern Medical Center in Dallas.  Dr. Frohman is also adjunct Professor of Behavioral and Brain Sciences as well as Professor of BioEngineering and Computer Science at the University of Texas at Dallas.  Dr. Frohman was born in New York City and received his undergraduate training in biochemistry and cell biology at the University of California at San Diego, and later completed the Physician Scientist Training Program for his M.D. and Ph.D. degrees at the University of California at Irvine.  Dr. Frohman subsequently completed his residency and fellowship training in the Department of Neurology at the Johns Hopkins University School of Medicine and the Johns Hopkins Hospital, where he is a former Chief Resident.  He is Board certified in psychiatry and neurology. Dr. Frohman has been the recipient of numerous awards and fellowships and has published papers in the areas of neuroimmunology, brain imaging, neuro-ophthalmology, neuro-otology, and neurourology.  In 2000, Dr. Frohman and his wife Teresa, authored a United States Congressional Appropriations Bill, which was sponsored by Senator Kay Bailey Hutchison (R-Texas), to establish a comprehensive Multiple Sclerosis Treatment Training Program at the University of Texas Southwestern School of Medicine, in collaboration with the National Multiple Sclerosis Society. The Program has  trained over 1,000 neurologists and neurology resident trainees from all 50 States. The Program was expanded to include advanced training for nurses and physician extenders in 2009.  Under Dr. Frohman and Teresa Frohman's leadership and mentorship, this innovative national education initiative focused on the multidisciplinary management of chronic neurologic illness, has represented a virtual pipeline for the development of young inellectual 'firepower'; where innumerable students, residents, and fellows have chosen to pursue careers as MS clinicians and clinical investigators.  Dr. Frohman has published over 250 peer-review articles, book chapters and monographs, and serves as a principal investigator on a number of MS clinical trials.  He also serves as reviewer for numerous journals including Annals of Neurology, Neurology, Archives of Neurology, Journal of Neurological Sciences, Journal of Neuroimmunology, Lancet, and Neuro-Ophthalmology. Dr. Frohman is married to Teresa Frohman, his closest colleague and principal collaborator for nearly 30 years (they have co-authored over 60 peer-review manuscripts together).  They have four children and live in Coppell, Texas.


Graduate School
University of California at Irvine (1988), Neurobiology
Medical School
University of California, Irvine - College of Medicine (1990)
University of Tennessee College of Medicine (1991), Internal Medicine
Johns Hopkins School of Medicine (1994), Neurology
Johns Hopkins School of Medicine (1995), Neurophysiology

Clinical Interest

Multiple Sclerosis & Inflammatory Disease of the Nervous System

  • Acute Demyelinating Encephalomyelitis (ADEM)
  • Devic's Disease (Neuromyelitis Optica)
  • Intranuclear Ophthalmoplegia (INO)
  • Multiple Sclerosis
  • Neurosarcoidosis
  • Optic Neuritis

Research Interest

  • Multiple Sclerosis Clinical Trials
  • Neuro-Ophthalmology
  • Neuroimmunology
  • Neuroprotection and Neurorestoration
  • Neuroradiology of MS
  • Neurorehabilitation
  • Retinohypothalamic Network
  • Sports Related Traumatic Brain Injury
  • Vestibular Neurology


Featured Publications LegendFeatured Publications

JC Virus in CD34+ and CD19+ Cells in Patients With Multiple Sclerosis Treated With Natalizumab.
Frohman EM, Monaco MC, Remington G, Ryschkewitsch C, Jensen PN, Johnson K, Perkins M, Liebner J, Greenberg B, Monson N, Frohman TC, Douek D, Major EO JAMA Neurol 2014 Mar
Injury to a specific neural pathway detected by ultra-high-field MRI.
Sakaie K, Takahashi M, Sagiyama K, Dimitrov I, Frohman T, Remington G, Frohman E, Fox RJ Neurology 2014 Jan 82 2 182-3
JC viremia in natalizumab-treated patients with multiple sclerosis.
Major EO, Frohman E, Douek D N. Engl. J. Med. 2013 Jun 368 23 2240-1
Uhthoff's phenomena in MS-clinical features and pathophysiology.
Frohman TC, Davis SL, Beh S, Greenberg BM, Remington G, Frohman EM Nat Rev Neurol 2013 Jun
Relationships between retinal axonal and neuronal measures and global central nervous system pathology in multiple sclerosis.
Saidha S, Sotirchos ES, Oh J, Syc SB, Seigo MA, Shiee N, Eckstein C, Durbin MK, Oakley JD, Meyer SA, Frohman TC, Newsome S, Ratchford JN, Balcer LJ, Pham DL, Crainiceanu CM, Frohman EM, Reich DS, Calabresi PA JAMA Neurol 2013 Jan 70 1 34-43


Featured Books Legend Featured Books

Honors & Awards

  • Excellence in Neurology Prize for my two students
    Mentored two UT Southwestern Medical Medical Students (Ethan Meltzer and Peter Squigna) who recently were awarded the Department of Neurology ≠urotherapeutics Neurology Award (the first time the award has been given jointly to two recipients; emphasizing the collaborative work of these two outstanding UT students) (2014-2014)
  • University of Texas Regents Outstanding Teacher Award (ROTA)- $25,000 cash prize
    Dr. Utilized this award to begin the Teresa Carol Frohman MS Initiative for Excellence in Patient Care, Education, and Discovery (2014-2014)
  • European Committee for Research and Treatment in MS [ECTRIMS]
    Mentored two UT Southwestern Medical Medical Students (Ethan Meltzer and Peter Squigna) who were awarded one of five ‘Best MS Research in 2013’ Prizes at the European Committee for the Treatment and Research of MS (ECTRIMS) among ~2,000 abstracts submitted Copenhagen Denmark (2013-2014)
  • Multiple Sclerosis Physician of Distinction
    Accelerated Cure Project's Best Physician of the Year (2012-2013)
  • US News and World Report
    List of Top Neurologists in the United States (2012-2014)
  • American Academy of Neurology
    National Teaching Award (AB Baker Section) (2008-2008)
  • Dallas Business Journal
    Health Care Hero Award (2008-2008)
  • Hadassah Doctor of the Year
  • Hall of Fame
    National Multiple Sclerosis Society Hall of Fame Award (2006-2006)
  • D Magazine's Best Doctors in Dallas Texas
    Best Neurologist (12 consecutive years) (2003-2014)
  • Fellow Status of the American Neurological Association
  • Fellow Status of the American Academy of Neurology
  • Congressional Appropriations Bill
    Authored a Congressional Bill to Establish a Natl MS Treatment Training Program (2001-2014)
  • Teaching Award
    Medical Students Excellence in Teaching Award (11-time recipient) 2000, 2001, 2003, 2004,2005, 2008, 2009, 2011, 2012, 2013, 2014 (2000-2014)
  • Teaching Award
    Resident Excellence in Teaching Award 1996, 1997, 2004 (1996-2004)
  • The Department of Neurology Award
    University of California at Irvine (1990-1990)
  • The University of California Academic Excellence Award
    For Academic Excellence and Promise as a Clinician Investigator (1990-1990)
  • Alpha Omega Alpha
    Medical Honor Society (1989-2014)
  • Exceptional Employee Award; Laboratory of Central Nervous System Studies
    National Institute of Neurological, Communicative Disorders & Stroke, National Institutes of Health (1987-1987)

Professional Associations/Affiliations

  • Adjunct Professor of Behavioral and Brain Sciences, UT Dallas (2014-2014)
  • Adjunct Professor of BioEngineering and Computer Science, UT Dallas (2014-2014)
  • Adjunct Professor of Neurology, Charles University, Prague, Czech Republic (2009-2014)
  • Alpha Omega Alpha (1989-2014)
  • American Academy of Neurology
  • American Medical Association
  • American Neurological Association