Undergraduate Wayne State University (1949)
Medical School Michigan State University (1953)

Specialty Areas

Clinical Interest

  • Adenocarcinoma
  • Bladder Cancer, Masses & Tumors
  • Prostate Cancer
  • Urothelial Cancer

Research Interest

  • Clinical therapeutic drug trials and
  • Drug resistance; and approaces for reversal of the malignant phenotype


Featured Publications LegendFeatured Publications

Lupus anticoagulant interference in activated protein C resistance testing: in vitro phenomenon or in vivo pathophysiologic effect?

Shen YM, Cimo ML, Bai Y, Frenkel E, Sarode R Clin. Appl. Thromb. Hemost. 2011 Nov-Dec 17 6 E190-5

The paradoxical effect of bevacizumab in the therapy of malignant gliomas.

Thompson EM, Frenkel EP, Neuwelt EA Neurology 2011 Jan 76 1 87-93

Thrombohemorrhagic defects associated with malignancy

Frenkel EP, Bick RL Lippincott Williams and Wilkins 2002 3rd Edition 265-282

Thrombocytopenia and thrombocytosis in: disorders of thrombosis and hemostasis: clinical and laboratory practice

Frenkel EP Lippincott Williams and Wilkins 2002 3rd Edition 91-115

Cobalamin Profiles in patients after urinary diversion

Sagalowsky AI, Frenkel EP J Urol 2002 167 1696-1700

Aberrant promoter methylation profile of prostate cancers and its relationship to clinical pathological features

Maruyama R, Toyooka S, Toyooka KO, Virmani AK, Zochbauer-Muller S, Farinas AJ, Minna JD, McConnell J, Frenkel EP, Gazdar Af Clin Cancer Research 2002 8 514-519

Enhanced transgene expression in androgen independent prostate cancer gene therapy by taxane chemotherapeutic agents

Li Y, Okegawa T, Lombardi DP, Frenkel EP, Hsieh JT J Urol 2002 167 339-346

Honors & Awards

  • Mastership
    American College of Physicians (2008)

Professional Associations/Affiliations

  • American Society for Clinical Investigation
  • American Society of Biological Chemists
  • American Society of Clinical Oncology
  • American Society of Hematology
  • Association of American Physicians