Medical School
University of Michigan Medical School (1953)
Wayne County General Hospital (1954), Intern
Boston City Hospital (1955), Internal Medicine
University of Michigan Medical School (1959), Internal Medicine
University of Michigan Medical School (1962), Hematology - Medical Oncology

Specialty Areas

Clinical Interest

  • Adenocarcinoma
  • Bladder Cancer, Masses & Tumors
  • Prostate Cancer
  • Urothelial Cancer
  • Research Interest

    • Clinical therapeutic drug trials and
    • Drug resistance; and approaces for reversal of the malignant phenotype


    Featured Publications LegendFeatured Publications

    Lupus anticoagulant interference in activated protein C resistance testing: in vitro phenomenon or in vivo pathophysiologic effect?
    Shen YM, Cimo ML, Bai Y, Frenkel E, Sarode R Clin. Appl. Thromb. Hemost. 2011 Nov-Dec 17 6 E190-5
    The paradoxical effect of bevacizumab in the therapy of malignant gliomas.
    Thompson EM, Frenkel EP, Neuwelt EA Neurology 2011 Jan 76 1 87-93
    Thrombohemorrhagic defects associated with malignancy
    Frenkel EP, Bick RL Lippincott Williams and Wilkins 2002 3rd Edition 265-282
    Thrombocytopenia and thrombocytosis in: disorders of thrombosis and hemostasis: clinical and laboratory practice
    Frenkel EP Lippincott Williams and Wilkins 2002 3rd Edition 91-115
    Cobalamin Profiles in patients after urinary diversion
    Sagalowsky AI, Frenkel EP J Urol 2002 167 1696-1700
    Aberrant promoter methylation profile of prostate cancers and its relationship to clinical pathological features
    Maruyama R, Toyooka S, Toyooka KO, Virmani AK, Zochbauer-Muller S, Farinas AJ, Minna JD, McConnell J, Frenkel EP, Gazdar Af Clin Cancer Research 2002 8 514-519
    Enhanced transgene expression in androgen independent prostate cancer gene therapy by taxane chemotherapeutic agents
    Li Y, Okegawa T, Lombardi DP, Frenkel EP, Hsieh JT J Urol 2002 167 339-346

    Honors & Awards

    • Mastership
      American College of Physicians (2008)

    Professional Associations/Affiliations

    • American Society for Clinical Investigation
    • American Society of Biological Chemists
    • American Society of Clinical Oncology
    • American Society of Hematology
    • Association of American Physicians