Nan Yan, Ph.D.

Assistant Professor

Endowed Title: Rita C. and William P. Clements, Jr. Scholar in Medical Research

Department: Internal Medicine, Microbiology

Graduate Programs: Immunology, Molecular Microbiology

Education

Undergraduate Fudan University - China (1999), Microbiology
Graduate School University of Texas at Austin (2006), Molecular Biology

Research Interests

  • Autoimmune diseases
  • HIV pathogenesis
  • Innate immunity
  • Retrovirology

Publications

Featured Publications Legend

Featured Publications

Cyclic GMP-AMP synthase is an innate immune sensor of HIV and other retroviruses.

Gao D, Wu J, Wu YT, Du F, Aroh C, Yan N, Sun L, Chen ZJ Science 2013 Aug 341 6148 903-6

SAMHD1 does it again, now in resting T cells.

Yan N, Lieberman J Nat. Med. 2012 Nov 18 11 1611-2

Intrinsic antiviral immunity.

Yan N, Chen ZJ Nat. Immunol. 2012 Mar 13 3 214-22

HIV DNA is heavily uracilated, which protects it from autointegration.

Yan N, O'Day E, Wheeler LA, Engelman A, Lieberman J Proc. Natl. Acad. Sci. U.S.A. 2011 May 108 22 9244-9

Gaining a foothold: how HIV avoids innate immune recognition.

Yan N, Lieberman J Curr. Opin. Immunol. 2011 Feb 23 1 21-8

The SET complex acts as a barrier to autointegration of HIV-1.

Yan N, Cherepanov P, Daigle JE, Engelman A, Lieberman J PLoS Pathog. 2009 Mar 5 3 e1000327

Identification of host proteins required for HIV infection through a functional genomic screen.

Brass AL, Dykxhoorn DM, Benita Y, Yan N, Engelman A, Xavier RJ, Lieberman J, Elledge SJ Science 2008 Feb 319 5865 921-6

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Honors/Awards

  • Endowed Scholar Award, UTSW
    (2011)
  • NIAID Career Development Award (K22)
    (2011)
  • Young Investigator Award, CORI
    (2008)
  • Center for AIDS Research (CFAR) Scholar Award
    (2007)