Research Interest

  • Energy Homeostasis
  • Epilepsy
  • Hypothalamic Development
  • Innate Behaviors
  • Serotonin


Featured Publications LegendFeatured Publications

Mutation of mouse Samd4 causes leanness, myopathy, uncoupled mitochondrial respiration, and dysregulated mTORC1 signaling.
Chen Z, Holland W, Shelton JM, Ali A, Zhan X, Won S, Tomisato W, Liu C, Li X, Moresco EM, Beutler B Proc. Natl. Acad. Sci. U.S.A. 2014 May 111 20 7367-72
PPAR? in Vagal Neurons Regulates High-Fat Diet Induced Thermogenesis.
Liu C, Bookout AL, Lee S, Sun K, Jia L, Lee C, Udit S, Deng Y, Scherer PE, Mangelsdorf DJ, Gautron L, Elmquist JK Cell Metab. 2014 Apr 19 4 722-30
Circuits Controlling Energy Balance and Mood: Inherently Intertwined or Just Complicated Intersections?
Liu C, Lee S, Elmquist JK Cell Metab. 2014 Mar
Arcuate AgRP neurons mediate orexigenic and glucoregulatory actions of ghrelin.
Wang Q, Liu C, Uchida A, Chuang JC, Walker A, Liu T, Osborne-Lawrence S, Mason BL, Mosher C, Berglund ED, Elmquist JK, Zigman JM Mol Metab 2014 Feb 3 1 64-72
Hepatocyte Toll-like receptor 4 regulates obesity-induced inflammation and insulin resistance.
Jia L, Vianna CR, Fukuda M, Berglund ED, Liu C, Tao C, Sun K, Liu T, Harper MJ, Lee CE, Lee S, Scherer PE, Elmquist JK Nat Commun 2014 5 3878
Serotonin 2C receptors in pro-opiomelanocortin neurons regulate energy and glucose homeostasis.
Berglund ED, Liu C, Sohn JW, Liu T, Kim MH, Lee CE, Vianna CR, Williams KW, Xu Y, Elmquist JK J. Clin. Invest. 2013 Dec 123 12 5061-70
Tipping the scales early: probing the long-term effects of obesity.
Liu C, Elmquist JK J. Clin. Invest. 2012 Nov 122 11 3840-2
Transcriptional control of serotonin-modulated behavior and physiology.
Liu C, Deneris ES Neuropsychopharmacology 2011 Jan 36 1 361-2
Substitution of 5-HT1A receptor signaling by a light-activated G protein-coupled receptor.
Oh E, Maejima T, Liu C, Deneris E, Herlitze S J. Biol. Chem. 2010 Oct 285 40 30825-36
Pet-1 is required across different stages of life to regulate serotonergic function.
Liu C, Maejima T, Wyler SC, Casadesus G, Herlitze S, Deneris ES Nat. Neurosci. 2010 Oct 13 10 1190-8

Honors & Awards

  • Pilot and Feasibility Award
    National Institute of Neurological Disease and Stroke (2015)
  • Scholarship Awards
    Keystone Symposium/Allen Institute for Brain Science (2014)
  • Doctoral Excellence Award
    Case Western Reserve University (2011)
  • Fellowship Award
    Davis Foundation in Eating Disorder Research (2011)
  • The President's Award
    Case Western Reserve University (2008)

Professional Associations/Affiliations

  • American Heart Association (2013)
  • Sigma Xi (2012)
  • American Association for the Advancement of Science (2008)
  • Society for Neuroscience (2008)