J Falck, Ph.D.

Undergraduate

Colorado State University (1970)

Graduate School

Colorado State University (1973)

• medicinal chemistry
• natural products isolation and identification
• organometalics
• synthetic methodology
• total synthesis

 Featured Publications

Picolinate Directed Arene meta-C-H Amination via FeCl₃ Catalysis.

Anugu RR, Munnuri S, Falck JR, J. Am. Chem. Soc. 2020 Feb

Development of Robust 17(R),18(S)-Epoxyeicosatetraenoic Acid (17,18-EEQ) Analogues as Potential Clinical Antiarrhythmic Agents.

Adebesin AM, Wesser T, Vijaykumar J, Konkel A, Paudyal MP, Lossie J, Zhu C, Westphal C, Puli N, Fischer R, Schunck WH, Falck JR, J. Med. Chem. 2019 Nov 62 22 10124-10143

Cu(II)-Mediated N-H and N-Alkyl Aryl Amination and Olefin Aziridination.

Munnuri S, Anugu RR, Falck JR, Org. Lett. 2019 Mar 21 6 1926-1929

Stereospecific Stille Cross-Couplings Using Mn(II)Cl2.

Dakarapu R, Falck JR J. Org. Chem. 2018 Jan

Cytochrome P450 monooxygenase lipid metabolites are significant second messengers in the resolution of choroidal neovascularization.

Hasegawa E, Inafuku S, Mulki L, Okunuki Y, Yanai R, Smith KE, Kim CB, Klokman G, Bielenberg DR, Puli N, Falck JR, Husain D, Miller JW, Edin ML, Zeldin DC, Lee KSS, Hammock BD, Schunck WH, Connor KM Proc. Natl. Acad. Sci. U.S.A. 2017 Aug

20-HETE Signals Through G Protein-Coupled Receptor GPR75 (Gq) to Affect Vascular Function and Trigger Hypertension

Garcia, V.; Gilani, A.; Shkolnik, B.; Pandey, V.; Zhang, F.F.; Dakarapu, R.; Gandham, S.K.; Reddy, N.R.; Graves, J.P.; Gruzdev, A.; Zeldin, D.C.; Capdevila, J.H.; Falck, J.R.; Schwartzman, M.L. Cir. Res. 2017 120 1776-1788

Dirhodium-catalyzed C-H arene amination using hydroxylamines.

Paudyal MP, Adebesin AM, Burt SR, Ess DH, Ma Z, Kürti L, Falck JR Science 2016 Sep 353 6304 1144-7

Direct Stereospecific Synthesis of Unprotected N-H and N-Me Aziridines from Olefins

Jat, J.L.; Paudyal, M.P.; Gao, H.; Xu, Q.-L.; Yousufuddin, M.; Devarajan, D.; Ess, D.H.; Kürti, L.; Falck, J.R. Science 2014 343 61-65

• American Chemical Society
  Wilfred T. Doherty Award (1996)
• Winter Eicosanoid Conference
  Special Recognition Award (1996)
• Phi Kappa Phi Honarary Society
  (1973)
• National Science Foundation
  Trainee (1970)

• American Chemical Society
• Royal Society of Chemistry (U.K.)