Graduate School Ohio State University-Main Campus (1999), Biochemistry
Graduate School Ohio State University-Main Campus (2002)

Research Interest

  • 1. Knowledge representation
  • 2. NGS and SNP data analysis
  • 3. High performance computing, C++
  • 4. Adaptive and innate immune systems
  • 5. Computational modeling and model validation
  • 6. Nucleic acids: synthesis, unwinding, repair
  • 7. Image analysis


Featured Publications LegendFeatured Publications

The protease domain increases the translocation stepping efficiency of the hepatitis C virus NS3-4A helicase.
Rajagopal V, Gurjar M, Levin MK, Patel SS J. Biol. Chem. 2010 Jun 285 23 17821-32
Experimental and computational analysis of DNA unwinding and polymerization kinetics.
Pandey M, Levin MK, Patel SS Methods Mol. Biol. 2010 587 57-83
Mechanism of cadmium-mediated inhibition of Msh2-Msh6 function in DNA mismatch repair.
Wieland M, Levin MK, Hingorani KS, Biro FN, Hingorani MM Biochemistry 2009 Oct 48 40 9492-502
Mechanism of ATP-driven PCNA clamp loading by S. cerevisiae RFC.
Chen S, Levin MK, Sakato M, Zhou Y, Hingorani MM J. Mol. Biol. 2009 May 388 3 431-42
Model-based global analysis of heterogeneous experimental data using gfit.
Levin MK, Hingorani MM, Holmes RM, Patel SS, Carson JH Methods Mol. Biol. 2009 500 335-59
Multiplexed RNA trafficking in oligodendrocytes and neurons.
Carson JH, Gao Y, Tatavarty V, Levin MK, Korza G, Francone VP, Kosturko LD, Maggipinto MJ, Barbarese E Biochim. Biophys. Acta 2008 Aug 1779 8 453-8
Multiplexed dendritic targeting of alpha calcium calmodulin-dependent protein kinase II, neurogranin, and activity-regulated cytoskeleton-associated protein RNAs by the A2 pathway.
Gao Y, Tatavarty V, Korza G, Levin MK, Carson JH Mol. Biol. Cell 2008 May 19 5 2311-27
Significant proportions of nuclear transport proteins with reduced intracellular mobilities resolved by fluorescence correlation spectroscopy.
Paradise A, Levin MK, Korza G, Carson JH J. Mol. Biol. 2007 Jan 365 1 50-65
A Brownian motor mechanism of translocation and strand separation by hepatitis C virus helicase.
Levin MK, Gurjar M, Patel SS Nat. Struct. Mol. Biol. 2005 May 12 5 429-35
DNA synthesis provides the driving force to accelerate DNA unwinding by a helicase.
Stano NM, Jeong YJ, Donmez I, Tummalapalli P, Levin MK, Patel SS Nature 2005 May 435 7040 370-3


Featured Books Legend Featured Books

Transient-state kinetics and computational analysis of transcription initiation. In Kinetic analysis of macromolecules a practical approach

S.S. Patel, R.P. Bandwar, M.K. Levin (2002). Oxford University Press

Helicases as Molecular Motors. In Molecular Motors

M.K. Levin, S.S. Patel (2004). Wiley-VCH Verlag GmbH & Co. KGaA