Featured Publications
Transition Step during Assembly of HIV Tat:P-TEFb Transcription Complexes and Transfer to TAR RNA.
D'Orso I, Jang GM, Pastuszak AW, Faust TB, Quezada E, Booth DS, Frankel AD Mol. Cell. Biol. 2012 Dec 32 23 4780-93
Transcription control by long non-coding RNAs.
Faust T, Frankel A, D'Orso I Transcription 2012 Mar 3 2
RNA-mediated displacement of an inhibitory snRNP complex activates transcription elongation.
D'Orso I, Frankel AD Nat. Struct. Mol. Biol. 2010 Jul 17 7 815-21
Global landscape of HIV-human protein complexes.
Jäger S, Cimermancic P, Gulbahce N, Johnson JR, McGovern KE, Clarke SC, Shales M, Mercenne G, Pache L, Li K, Hernandez H, Jang GM, Roth SL, Akiva E, Marlett J, Stephens M, D'Orso I, Fernandes J, Fahey M, Mahon C, O'Donoghue AJ, Todorovic A, Morris JH, Maltby DA, Alber T, Cagney G, Bushman FD, Young JA, Chanda SK, Sundquist WI, Kortemme T, Hernandez RD, Craik CS, Burlingame A, Sali A, Frankel AD, Krogan NJ Nature 2012 Jan 481 7381 365-70
Purification and characterization of HIV-human protein complexes.
Jäger S, Gulbahce N, Cimermancic P, Kane J, He N, Chou S, D'Orso I, Fernandes J, Jang G, Frankel AD, Alber T, Zhou Q, Krogan NJ Methods 2011 Jan 53 1 13-9
HIV-1 Tat: Its Dependence on Host Factors is Crystal Clear.
D'Orso I, Frankel AD Viruses 2010 Oct 2 10 2226-2234
Host cell factors in HIV replication: meta-analysis of genome-wide studies.
Bushman FD, Malani N, Fernandes J, D'Orso I, Cagney G, Diamond TL, Zhou H, Hazuda DJ, Espeseth AS, König R, Bandyopadhyay S, Ideker T, Goff SP, Krogan NJ, Frankel AD, Young JA, Chanda SK PLoS Pathog. 2009 May 5 5 e1000437
Tat acetylation modulates assembly of a viral-host RNA-protein transcription complex.
D'Orso I, Frankel AD Proc. Natl. Acad. Sci. U.S.A. 2009 Mar 106 9 3101-6
Targeting tat inhibitors in the assembly of human immunodeficiency virus type 1 transcription complexes.
D'Orso I, Grunwell JR, Nakamura RL, Das C, Frankel AD J. Virol. 2008 Oct 82 19 9492-504
A solution to limited genomic capacity: using adaptable binding surfaces to assemble the functional HIV Rev oligomer on RNA.
Daugherty MD, D'Orso I, Frankel AD Mol. Cell 2008 Sep 31 6 824-34
