James De Lemos, M.D.

Associate Program Director, Cardiology Fellowship Program

Professor

Endowed Title: Sweetheart Ball - Kern Wildenthal, M.D., Ph.D., Distinguished Chair in Cardiology

Department: Internal Medicine

Biography

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Dr. de Lemos is Professor of medicine and holds the Sweetheart Ball-Kern Wildenthal, MD, PhD Distinguished Chair in Cardiology.  He is the Cardiology Service Chief at Parkland Memorial Hospital where he also serves as CCU Director.  He was the director of the Cardiology Fellowship at UT Southwestern from 2005-2011. He is an active investigator in the Donald W. Reynolds Cardiovascular Research Center at UT Southwestern, and the Medical Director of the Dallas Heart Study.   He has chaired or co-chaired several research planning committees at UT Southwestern.  His primary research interests are in early detection, risk assessment and management of cardiovascular disease, with a particular focus on the role of cardiovascular biomarkers.  His research has evaluated existing biomarkers such as B-type natriuretic peptide, C-reactive protein and cardiac troponins as well as novel biomarkers reflecting biological pathways of disease.  He was the lead author of the Z phase of the A to Z trial, an international trial investigating different cholesterol lowering strategies in patients with acute coronary syndromes.  He graduated from Harvard Medical School and completed an Internal Medicine Residency at UT Southwestern Medical Center, where he also served as Chief Medical Resident.  He completed a fellowship in Cardiovascular Medicine and served on the faculty at the Brigham and Women’s Hospital before returning to UT Southwestern Medical School.  He has served on multiple committees of the AHA and ACC and is on the editorial board of the Journal of the American College of Cardiology, the American Journal of Cardiology and the American Heart Journal.  He has mentored >25 post-doctoral research trainees and has authored or coauthored over 250 manuscripts or book chapters and won several teaching awards. He sees patients with a broad range of cardiac problems, but specializes in those with chest pain and coronary artery disease.

Education

Medical School Harvard Medical School (1992)
Internship UT Southwestern Medical Center (1993), Internal Medicine
Residency UT Southwestern Medical Center (1995), Internal Medicine
Chief Resident UT Southwestern Medical Center (1996), Internal Medicine
Fellowship Harvard Medical School (1999), Cardiology

Clinical Interests

Clinical Cardiology
  • Abnormal Cholesterol
  • Angina Pectoris
  • Atrial Fibrillation & Flutter
  • Cardiomyopathy
  • Chest Pain
  • Congestive Heart Disease
  • Coronary Artery Disease
  • Heart Murmur
  • Heart Palpitations
  • Hypertension (High Blood Pressure)
  • Initial Cardiology Consultations
  • Non-Invasive Cardiovascular Testing
  • Second Opinions for Heart Disease
  • Syncope (Fainting)

Research Interests

  • Acute Coronary Syndromes
  • Cardiac Biomarkers
  • Lipid Lowering Therapy
  • Screening for Cardiovascular Disease

Publications

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Featured Publications

Low levels of circulating troponin as an intermediate phenotype in the pathway to heart failure.

de Lemos JA, Grundy SM J. Am. Coll. Cardiol. 2012 Jan 59 5 490-2

Association of growth differentiation factor-15 with coronary atherosclerosis and mortality in a young, multiethnic population: observations from the Dallas Heart Study.

Rohatgi A, Patel P, Das SR, Ayers CR, Khera A, Martinez-Rumayor A, Berry JD, McGuire DK, de Lemos JA Clin. Chem. 2012 Jan 58 1 172-82

No free lunches: balancing bleeding and efficacy with ticagrelor.

de Lemos JA, Brilakis ES Eur. Heart J. 2011 Dec 32 23 2919-21

Race-specific associations of myeloperoxidase with atherosclerosis in a population-based sample: the Dallas Heart Study.

Chen LQ, Rohatgi A, Ayers CR, Das SR, Khera A, Berry JD, McGuire DK, de Lemos JA Atherosclerosis 2011 Dec 219 2 833-8

Results 1-10 of 116

Books

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Featured Books

Honors/Awards

  • Simon Dack Award for Medical Publications
    Journal of the American College of Cardiology (2012)
  • Association of University Cardiologists
    (2011)
  • Best Doctors in Dallas, Cardiology
    D Magazine (2011)
  • Core Clerkship Teaching Award
    UT Southwestern (2011)
  • Super Doctors, Cardiology
    Texas Monthly (2011)
  • Best Doctors in Dallas, Cardiology
    D Magazine (2010)
  • Super Doctors, Cardiology
    Texas Monthly (2010)
  • Sweetheart Ball-Kern Wildenthal MD, PhD Distinguished Chair
    Distinguished Chair in Cardiology (2009)
  • Elite Reviewer
    Journal of the American College of Cardiology (2006)
  • Best Doctors in Dallas, Cardiology
    D Magazine (2005)
  • Internal Medicine Teaching Award
    Excellence in Teaching (2005)
  • Eugene Braunwald Fellowship
    Excellence in Clinical Research, Brigham and Women’s Hospital (1999)
  • Soma Weiss Award
    Excellence in Teaching, Brigham and Women’s Hospital (1997)

Professional Associations/Affiliations

  • Society of Chest Pain Physicians (2011)
  • AHA/ACC ST Elevation MI Guideline Committee (2010-2012)
  • Chair, Research and Publications Committee (2010)
  • American Heart Association (1998)
  • American College of Cardiology (1996)