|Undergraduate||University of Kansas Main Campus (1995), Arts|
|Graduate School||University of Kansas Medical Center (2006), Physiology|
- B cell contribution to stroke injury and repair
- chemokine expression
- neuronal plasticity
- vascular inflammation
- Repetitive hypoxic preconditioning induces an immunosuppressed B cell phenotype during endogenous protection from stroke.
- Monson NL, Ortega SB, Ireland SJ, Meeuwissen AJ, Chen D, Plautz EJ, Shubel E, Kong X, Li MK, Freriks LH, Stowe AM J Neuroinflammation 2014 Jan 11 1 22
- Functional near-infrared spectroscopy maps cortical plasticity underlying altered motor performance induced by transcranial direct current stimulation.
- Khan B, Hodics T, Hervey N, Kondraske G, Stowe AM, Alexandrakis G J Biomed Opt 2013 Nov 18 11 116003
- Elevated CNS inflammation in patients with preclinical Alzheimer's disease.
- Monson NL, Ireland SJ, Ligocki AJ, Chen D, Rounds WH, Li M, Huebinger RM, Munro Cullum C, Greenberg BM, Stowe AM, Zhang R J. Cereb. Blood Flow Metab. 2013 Oct
- CCL2 upregulation triggers hypoxic preconditioning-induced protection from stroke.
- Stowe AM, Wacker BK, Cravens PD, Perfater JL, Li MK, Hu R, Freie AB, Stüve O, Gidday JM J Neuroinflammation 2012 9 33
- Repetitive hypoxia extends endogenous neurovascular protection for stroke
- Stowe AM, Altay T Freie AB, and Gidday JM Annals of Neurology 2011 69 6
- A pilot study to measure upper extremity H-reflexes following neuromuscular electrical stimulation therapy after stroke.
- Stowe AM, Hughes-Zahner L, Barnes VK, Herbelin LL, Schindler-Ivens SM, Quaney BM Neurosci. Lett. 2013 Feb 535 1-6
- Neutrophil elastase and neurovascular injury following focal stroke and reperfusion.
- Stowe AM, Adair-Kirk TL, Gonzales ER, Perez RS, Shah AR, Park TS, and Gidday JM Neurobiol Dis. July 2009 35 82-90
- Early and late changes in the distal forelimb representation of the supplementary motor area following injury to frontal motor areas in the squirrel monkey.
- Eisner-Janowicz I, Barbay S, Hoover E, Stowe AM, Frost SB, Plautz EJ, and Nudo RJ J Neurophys September 2008 100 1498-512.
- Between-day reliability of upper extremity h-reflexes.
- Stowe AM, Hughes-Zahner L, Stylianou AP, Schindler-Ivens S, and Quaney BM J Neurosci Meth. May 2008 30 317-23
- Neuronal HIF-1a protein and VEGFR-2 immunoreactivity in functionally related motor areas following a focal M1 infarct.
- Stowe AM, Plautz EJ, Nguyen P, Frost SB, Eisner-Janowicz I, Barbay S, Dancause N, Sensarma A, Taylor M, Zoubina EV, and Nudo RJ J Cereb Blood Flow Metab. March 2007 28 (3) 612-20
Honors & Awards
- Big D Tackling Alzheimers Award (co-PI)
This study, funded by our local non-profit with donations from the annual BvB Powder Puff football game at the Cotton Bowl, will look at how an cardiovascular exercise regimen in patients with Alzheimers disease affects inflammation, the adaptive immune system, and quality of life. (2015-2015)
- R01 NIH/NINDS 5R01NS088555 (PI)
This proposed research will be the first to determine how the transfer of B cells as a post-stroke neurotherapeutic directly interacts with neurons to reduce injury and improve recovery, and how this therapy alters a previously unstudied post-stroke autoimmune response that contributes to neuronal protection. (2015-2020)
- American Heart Association Grant-in-Aid (co-I)
The long-range objectives of this grant are to determine if dTDCS-enhanced rehabilitation after hemorrhagic strokes induces long-term functional recovery, and to collect pilot data to quantify the contribution of genetic polymorphisms in the vascular endothelial growth factor (VEGF) to post-stroke cortical plasticity. (2014-2015)
- American Heart Association National Scientist Development grant (PI)
The long-range objective of this grant is to elucidate B cell-mediated adaptive immune mechanisms during neurovascular protection following repetitive hypoxic preconditioning, and whether this protection is transferable with a B cell therapy in mice. (2014-2017)
- American Physiological Society, Early Career Advocacy Fellowship
- Clinical Research, NIH/NINDS Loan Repayment Program
The long-term objectives of my ongoing clinical research are to study mechanisms underlying post-stroke recovery. This includes collaborations with clinical researchers to determine the influence of growth factor genetic polymorphisms on the response to transcranial direct current stimulation (tDCS), and to develop a novel system to monitor cortical plasticity during rehabilitation plus tDCS in stroke patients. (2013-2015)
- Member, American Heart Association (2010)
- Member, International Society for Cerebral Blood Flow and Metabolism (2007)
- Member, Society for Neuroscience (2001)
- Member, American Physiological Society (2000)