Taekyung Kim, Ph.D.

Assistant Professor

Endowed Title: Distinguished Scholar in Neuroscience

Department: Neuroscience

Graduate Programs: Genetics and Development, Neuroscience

Biography

Dr. Kim graduated from Korea University in South Korea with a bachelor degree in biology. During graduate study at the University of Medicine & Dentistry of New Jersey (formerly Rutgers University Medical School at Piscataway, NJ), he studied the molecular mechanisms and regulation of eukaryotic gene expression under the supervision of Dr. Danny Reinberg (HHMI, currently at NYU).

After obtaining a PhD degree in Biochemistry, he continued his research career in the laboratory of Dr. Michael Greenberg (Harvard Medical School) as a postdoctoral fellow, studying how neuronal activity controls gene expression in neurons to mediate synapse remodeling and plasticity.

Dr. Kim joined the faculty in the Department of Neuroscience at UT Southwestern in 2010.

Education

Undergraduate Korea University (1993), Biology
Graduate School University of Medicine and Dentistry of New Jersey (2000), Biomedical Studies

Research Interests

  • Characterization of neuronal enhancers that control temporal and spatial-specific gene expression in brain
  • Global analysis of activity-regulated gene expression and epigenetic program in brain
  • Understanding the function of a novel class of noncoding RNAs that are expressed in brain

Publications

Featured Publications Legend

Featured Publications

Systematic evaluation of factors influencing ChIP-seq fidelity.

Chen Y, Negre N, Li Q, Mieczkowska JO, Slattery M, Liu T, Zhang Y, Kim TK, He HH, Zieba J, Ruan Y, Bickel PJ, Myers RM, Wold BJ, White KP, Lieb JD, Liu XS Nat. Methods 2012 Jun 9 6 609-14

Bhlhb5 and Prdm8 form a repressor complex involved in neuronal circuit assembly.

Ross SE, McCord AE, Jung C, Atan D, Mok SI, Hemberg M, Kim TK, Salogiannis J, Hu L, Cohen S, Lin Y, Harrar D, McInnes RR, Greenberg ME Neuron 2012 Jan 73 2 292-303

Widespread transcription at neuronal activity-regulated enhancers

Tae-Kyung Kim, Hemberg M, Gray JM, Costa AM, Bear DM, Wu J, Harmin DA, Laptewicz M, Barbara-Haley K, Kuersten S, Markenscoff-Papadimitriou E, Kuhl D, Bito H, Worley PF, Kreiman G, Greenberg ME Nature (Article); **News and Views in Nature. 2010 May 13;465(7295):173-4. May 2010 465 182-7

The Angelman Syndrome Protein Ube3A Regulates Synapse Development by Ubiquitinating Arc

Greer PL, Hanayama R, Bloodgood BL, Mardinly AR, Lipton DM, Flavell SW, Tae-Kyung Kim, Griffith EC, Waldon Z, Maehr R, Ploegh HL, Chowdhury S, Worley PF, Steen J, Greenberg ME Cell 2010 140(5) 704-716

A retrograde neuronal survival response: target-derived neurotrophins regulate MEF2D and bcl-w

Pazyra-Murphy MF, Hans A, Karch C, Courchesne S, Heerssen HM, Watson FL, Tae-Kyung Kim, Greenberg ME, Segal RA J. Neurosci. 2009 29(20) 6700-6709

Results 1-10 of 12

Honors/Awards

  • The Klingenstein Fellowship Award
    (2012)
  • The Welch Foundation
    (2012)
  • Whitehall foundation
    (2011)
  • Regent’s Research Scholar Award, UT Southwestern
    (2010)
  • Jane Coffin Childs Memorial Fund for Medical Research
    (2003)
  • Lefler Fellowship, Harvard Medical School
    (2002)
  • Deans Award for Excellence in Studies, Korea University
    (1993)