Jing Tian, Ph.D.
Assistant Professor
School Medical School
Department Molecular Genetics
Education
- Graduate School
- Cornell University Medical Col (2006), Biochemistry
Research Interest
- Gene regulation and protein post-translational modification
- Insulin cascade and mTOR pathway
- Lipid metabolism
- Obesity, diabetes and cardiovascular disease
Publications
Featured Publications
- BHLHE40, a third transcription factor required for insulin induction of SREBP-1c mRNA in rodent liver.
- Tian J, Wu J, Chen X, Guo T, Chen ZJ, Goldstein JL, Brown MS Elife 2018 Jun 7
- Insulin induction of SREBP-1c in rodent liver requires LXRa-C/EBP? complex.
- Tian J, Goldstein JL, Brown MS Proc. Natl. Acad. Sci. U.S.A. 2016 Jul 113 29 8182-7
- S-nitrosylation/activation of COX-2 mediates NMDA neurotoxicity.
- Tian J, Kim SF, Hester L, Snyder SH Proc. Natl. Acad. Sci. U.S.A. 2008 Jul 105 30 10537-40
- The cationic amino acid transporters CAT1 and CAT3 mediate NMDA receptor activation-dependent changes in elaboration of neuronal processes via the mammalian target of rapamycin mTOR pathway.
- Huang Y, Kang BN, Tian J, Liu Y, Luo HR, Hester L, Snyder SH J. Neurosci. 2007 Jan 27 3 449-58
- Mycobacterium tuberculosis appears to lack alpha-ketoglutarate dehydrogenase and encodes pyruvate dehydrogenase in widely separated genes.
- Tian J, Bryk R, Shi S, Erdjument-Bromage H, Tempst P, Nathan C Mol. Microbiol. 2005 Aug 57 3 859-68
- Variant tricarboxylic acid cycle in Mycobacterium tuberculosis: identification of alpha-ketoglutarate decarboxylase.
- Tian J, Bryk R, Itoh M, Suematsu M, Nathan C Proc. Natl. Acad. Sci. U.S.A. 2005 Jul 102 30 10670-5