Uttam Tambar is an organic chemist with an interest in biomedical research. He received his AB degree from Harvard University in 2000, and his PhD from the California Institute of Technology in 2006. He was an NIH Postdoctoral Fellow at Columbia University (2006-2009). He began his independent research career in 2009 at UT Southwestern.
Dr. Tambar is interested in developing new strategies and concepts in synthetic chemistry to address challenging problems in biomedical research. In addition to making fundamental advances in chemistry, he will take advantage of the unique opportunities for collaborative research at UT Southwestern.
Laboratory Website: http://www4.utsouthwestern.edu/tambarlab
- Graduate School
- Harvard University (2000), Chemistry
- Graduate School
- California Institute of Techno (2006), Organic Chemistry
- Development of new chemical reactions
- Discovery of small molecule drugs
- Synthesis of complex biologically active natural products
- Catalytic allylic oxidation of internal alkenes to a multifunctional chiral building block.
- Bayeh L, Le PQ, Tambar UK Nature 2017 Jun
- Copper-Catalyzed Enantioselective, Diastereoselective, and Regioselective [2,3]-Rearrangements of Iodonium Ylides.
- Xu B, Tambar UK Angew. Chem. Int. Ed. Engl. 2017 Jun
- Copper-Catalyzed Aminothiolation of 1,3-Dienes via a Dihydrothiazine Intermediate.
- Sleet CE, Tambar UK Angew. Chem. Int. Ed. Engl. 2017 Apr
- Ligand-Controlled Regiodivergence in the Copper-Catalyzed [2,3]- and [1,2]-Rearrangements of Iodonium Ylides.
- Xu B, Tambar UK J. Am. Chem. Soc. 2016 Sep 138 37 12073-6
- Isoform-Selective and Stereoselective Inhibition of Hypoxia Inducible Factor-2.
- Scheuermann TH, Stroud D, Sleet CE, Bayeh L, Shokri C, Wang H, Caldwell CG, Longgood J, MacMillan JB, Bruick RK, Gardner KH, Tambar UK J. Med. Chem. 2015 Jul
- Regioselective and Diastereoselective Aminoarylation of 1,3-Dienes.
- Bao H, Bayeh L, Tambar UK Chem Sci 2014 Dec 5 12 4863-4867
- Allylic functionalization of unactivated olefins with grignard reagents.
- Bao H, Bayeh L, Tambar UK Angew. Chem. Int. Ed. Engl. 2014 Feb 53 6 1664-8
Honors & Awards
- Sloan Foundation Research Fellowship
- W. W. Caruth, Jr. Scholar in Biomedical Research
- NIH Ruth L. Kirschstein NRSA Postdoctoral Fellow
- National Defense Science and Engineering Graduate Fellow
- John Harvard Scholar
- American Chemical Society (2000)