Ian Corbin, Ph.D.

Dr. Ian Corbin received his Bachelor’s of Science degree in 1994 from the University of Winnipeg, Canada. He then went on to earn a Masters of Science from the University of Manitoba in the Department of Anatomy and Cell Sciences where he used high resolution NMR to study metabolic interactions between parasitic cestodes and their murine hosts.  Thereafter, Dr. Corbin continued at the University of Manitoba to earn his doctorate in Pharmacology and Therapeutics in 2002. His thesis dissertation focused on the use of in vivo ³¹P MRS as a diagnostic tools for assessing the severity of liver disease. After completing his PhD Dr. Corbin spent four years as a Postdoctoral Fellow at the University of Pennsylvania in the Department of Radiology where he began working in the field of nanotechnology.  In 2006, he was appointed as a Scientific Associate at the University Health Network, Division of Biophysics and Bioimaging, Toronto, Canada. At this center Dr. Corbin continued to develop expertise and expand his investigations in the area of diagnostic and therapeutic nanomedicine. In 2009, Dr. Corbin returned to the United States where he accepted a position as an Assistant Professor in the Advanced Imaging Research Center at the University of Texas Southwestern Medical Center.

Undergraduate	University of Winnipeg (1994)
Graduate School	University of Manitoba (1997), Anatomy
Graduate School	University of Manitoba (2002), Pharmacology

• Hepatocellular Carcinoma
• Liver Disease
• Magnetic Resonance Spectroscopy
• Molecular Imaging
• Nanomedicine

Featured Publications

Enhanced Cancer-targeted Delivery Using Engineered High-Density Lipoprotein-Based Nanocarriers

Corbin I.R., J. Chen, W. Cao, H. Li, S. Lund-Katz, G. Zheng Journal of Biomedical Nanotechnology 2007 3 367-376

Low Density Lipoprotein Nanoparticles as magnetic Resonance Imaging Contrast Agents.

Corbin I.R., H. Li, J. Chen, S. Lund-katz, R. Zhou, J.D. Glickson, G. Zheng Neoplasia 2006 6/8 488-498

Utility of hepatic phosphorus-31 magnetic resonance spectroscopy in a rat model of acute liver failure.

Corbin I.R., R. Buist, J. Peeling, M. Zhang, J. Uhanova and G.Y. Minuk Journal of Investigative Medicine 2003 51 42-49

Examination of regenerative activity and liver function following partial hepatectomy in the rat utilizing hepatic phosphorus-31 magnetic resonance spectroscopy

Corbin I.R., R. Buist, V. Volotovsky, J. Peeling, M. Zhang and G.Y. Minuk Hepatology 2002 36 345-353

In vivo assessment of hepatic triglycerides in murine non-alcoholic fatty liver disease using magnetic resonance spectroscopy.

Corbin I.R., S. Pickup, E. Furth and E.J. Delikatny Biochimica et Biophysica Acta 2009 8/1791 757-763

Biomimetic Nanocarrier for Direct Cytosolic Drug Delivery

Zhang Z., W. Cao, H. Jin, J.F. Lovell, M. Yang, L.Ding, J. Chen, I. Corbin, Q. Luo, G. Zheng Angewandte Chemie 2009

Ligand Conjugated Low-density Lipoprotein Nanoparticles for Enhanced Optical Cancer Imaging in Vivo

Chen J., I.R. Corbin, H. Li, W. Cao, J.D. Glickson , G. Zheng Journal of American Chemical Society 2007 18/129 5798-5799

Enhanced Cancer-targeted Delivery Using Engineered High-Density Lipoprotein-Based Nanocarriers

Corbin I.R., J. Chen, W. Cao, H. Li, S. Lund-Katz, G. Zheng Journal of biomedical Nanotechnology 2007 3 367-376

• American Gastroenterological Association Research Scholar Award Grant
  (2010)
• UTSW President’s Research Council Award
  (2010)
• MMSF Morris Neaman-Norman and Margaret Corne Major Research Award
  (2003)
• University of Manitoba E.L. Drewry Research Award
  (2003)
• University of Manitoba Health Sciences Dissertation Award
  (2003)
• Glaxo Wellcome/CASL Hepatology Fellowship
  (2002)
• Canadian Liver Foundation Graduate Studentship Award
  (2000)