Andrew Koh, M.D. Titles and Appointments Chief, Division of Pediatric Hematology and Oncology Professor & Division Chief Endowed Title Grant A. Dove Distinguished Chair for Research in Oncology Schools Medical School | Graduate School Departments Pediatrics | Harold C. Simmons Comprehensive Cancer Center | Microbiology Graduate Programs Immunology, Molecular Microbiology You have reached the Academic Profile. For more information on the doctor and patient care, please visit the clinical profile. Biography Download Curriculum Vitae Dr. Andrew Y. Koh received his bachelor’s degree in Biology from Harvard College. He was then awarded a Rhodes Scholarship and received a B.A. in English Literature at Pembroke College, Oxford University. Dr. Koh obtained his MD degree from Harvard Medical School. He completed internship, residency, and chief residency at Children’s Hospital, Boston. He then completed a dual fellowship in hematology/oncology and infectious diseases at Children’s Hospital, Boston, and Dana Farber Cancer Institute. Dr. Koh left Harvard to become Director of Pediatric Hematopoeitic Stem Cell Transplantation at the University of Texas Southwestern Medical Center in 2009. He is currently Professor and Division Chief of Pediatric Hematology/Oncology and holds the Grant A. Dove Distinguished Chair for Research in Oncology. The Koh Lab focuses on understanding how the gut microbiome influences host immune responses in cancer and stem cell transplant patients. Specific projects include bacterial/fungal infections originating from the gut, autoimmune complications (e.g. graft-versus host disease), the evolution of antibiotic resistance in the mammalian gut, and host immune anti-tumor response. Recent work has focused on developing novel gut microbiome-derived therapeutics for enhancing cancer immunotherapy efficacy -- efforts that have resulted in the filing of two patents, receipt of NIH and industry funding, and co-founding of a startup company, Aumenta Biosciences. Education Medical School Harvard Medical School (1996) Residency Children's Hospital of Boston - Pediatric Program (1999), Pediatric Medicine Residency Children's Hospital of Boston - Pediatric Program (2000), Pediatric Medicine Fellowship Children's Hospital Boston - Hematology/Oncology (2004), Pediatric Hematology/oncology Fellowship Children's Hospital Boston - Infectious Disease (2004), Pediatric Infectious Diseases Research Interest Antibiotic Resistance Cancer immunotherapy Candida albicans pathogenesis Gut microbiome Gut Microbiota (bacterial-fungal interactions) Host immune anti-tumor response Host pathogen interactions Intestinal graft-versus-host-disease Publications Feasibility of Atezolizumab in Combination With Chemotherapy for Children With Relapsed or Refractory Solid Tumors Campbell ME, Stutzman S, Primeaux S, Sida D, Lee M, Shah AT, Sadanand A, Sokol E, Collins NB, Turpin B, Navai S, Albert K, Laetsch TW, Rakheja D, Chen KS, Gerber DE, Koh AY Pediatric Blood and Cancer 2025 Dec 72 Identifying Microbiota and Immune Host Factors Associated With Bleeding Risk in Children With Immune Thrombocytopenia Saini S, Sabaeifard P, Coughlin L, Poulides N, Gan S, Zhan X, Dang M, Koh AY, Zia A American Journal of Hematology 2025 Jun 100 1090-1093 A fungal ally wards off liver disease Hooper LV, Koh AY Science 2025 May 388 470-471 Optimizing Precision Probiotics for Mitigating Graft-Versus-Host Disease Ebigbo N, Long A, Do P, Coughlin L, Poulides N, Jewell T, Gan S, Zhan X, Koh AY Microorganisms 2025 Apr 13 Assessment of Distinct Gut Microbiome Signatures in a Diverse Cohort of Patients Undergoing Definitive Treatment for Rectal Cancer Hein DM, Coughlin LA, Poulides N, Koh AY, Sanford NN Journal of Immunotherapy and Precision Oncology 2024 Aug 7 150-158 Breathe and bloom: Gut hypoxia limits C. albicans growth Mishra AA, Koh AY Cell Host and Microbe 2024 Jul 32 1041-1043 Susceptible bacteria can survive antibiotic treatment in the mammalian gastrointestinal tract without evolving resistance Rodrigues M, Sabaeifard P, Yildiz MS, Lyon A, Coughlin L, Ahmed S, Poulides N, Toprak AC, Behrendt C, Wang X, Monogue M, Kim J, Gan S, Zhan X, Filkins L, Williams NS, Hooper LV, Koh AY, Toprak E Cell Host and Microbe 2024 Mar 32 396-410.e6 Precision modulation of dysbiotic adult microbiomes with a human-milk-derived synbiotic reshapes gut microbial composition and metabolites Button JE, Cosetta CM, Reens AL, Brooker SL, Rowan-Nash AD, Lavin RC, Saur R, Zheng S, Autran CA, Lee ML, Sun AK, Alousi AM, Peterson CB, Koh AY, Rechtman DJ, Jenq RR, McKenzie GJ Cell Host and Microbe 2023 Sep 31 1523-1538.e10 Immune checkpoint blockade induces gut microbiota translocation that augments extraintestinal antitumor immunity Choi Y, Lichterman JN, Coughlin LA, Poulides N, Li W, Del Valle P, Palmer SN, Gan S, Kim J, Zhan X, Gao Y, Evers BM, Hooper LV, Pasare C, Koh AY Science Immunology 2023 Mar 8 IsoAnalytics: A single-cell proteomics web server Palmer SN, Koh AY, Zhan X Bioinformatics Advances 2023 3 Results 1-10 of 73 1 2 3 4 5 Next Last Books Featured Books Fever and Granulocytopenia; Infections in Children with Cancer. In Long SS, Pickering LK, Prober CG, eds. Principles and Practice of Pediatric Infectious Diseases. 6th ed. Ardura M, Koh AY (2022). Elsevier Saunders Infectious Complications in Pediatric Cancer Patients. In Susan M. Blaney MD, Lee J. Helman MD, Peter C. Adamson MD, eds. Pizzo & Poplack's Pediatric Oncology. 8th ed. Ardura MI, Koh AY. (2020). Philadelphia: Wolters Kluwer; Honors & Awards Basil O'Connor Research Award (March of Dimes) (2013-2015) Eleanor and Miles Shore Scholar (2006-2008) Glaser Pediatric Research Network Fellowship Award (2000-2002) Rhodes Scholarship (1988-1990) Professional Associations/Affiliations American Society for Blood and Marrow Transplantation (2009) American Society for Microbiology (2003) American Society for Pediatric Hematology/Oncology (2012) American Society of Hematology (2010) Society for Pediatric Research (2010)
