Jeffrey S. Kahn, M.D.-Ph.D. received his Bachelor of Science degree in Microbiology and Immunology from McGill University. He received his M.D. and a Ph.D. in Microbiology and Immunology from the State University of New York Health Science Center at Brooklyn. Dr. Kahn completed his internship, residency and chief residency in Pediatrics at Yale University and the Children’s Hospital at Yale-New Haven Hospital. Dr. Kahn stayed at Yale University to complete training in Pediatric Infectious Diseases. Thereafter, he joined the faculty at Yale University in the Department of Pediatrics in the Division of Infectious Diseases. He joined the faculty of UT Southwestern Medical Center in 2009.
Dr. Kahn’s research efforts have been focused human respiratory viruses, including respiratory syncytial virus (RSV) and new emerging human viruses. His laboratory was the first or among the first laboratories in the United States to describe the epidemiology and clinical manifestations of several newly identified viruses including human metapneumovirus, coronaviruses NL63 and HKU1, human bocavirus and polyomavirus WUV. His laboratory has described the molecular epidemiology of RSV and has characterized the glycoprotein sequences, completed phylogenetic analyses and defined the biological properties (e.g. induction of cytokines and chemokines) and induced gene expression profiles (using RNA-SEQ) of many of these RSV strains in primary human cells. Dr. Kahn’s current research efforts are focuses on mapping RSV phenotypes in the viral genome.
Dr. Kahn is the Director of the Pediatric Infectious Disease and the Pediatric Infectious Diseases Fellowship Program at UT Southwestern Medical Center and the Director of Infectious Diseases at Children’s Medical Center. Dr. Kahn is the Medical Director of Research at Children’s Medical Center.
- Medical School
- SUNY Health Science Center at Brooklyn College of Medicine (1991)
- Yale-New Haven Hospital (1994), Pediatrics
- Chief Resident
- Yale-New Haven Hospital (1995), Pediatrics
- Yale University School of Medicine (1998), Pediatric Infectious Diseases
- Cellular responses to RSV infection
- Emerging pathogens
- Recombinant negative stand RNA viruses
- Respiratory syncytial virus
- Distinct patterns of innate immune activation by clinical isolates of respiratory syncytial virus.
- Levitz R, Gao Y, Dozmorov I, Song R, Wakeland EK, Kahn JS PLoS ONE 2017 12 9 e0184318
- Inpatient Bronchiolitis Guideline Implementation and Resource Utilization.
- Mittal V, Darnell C, Walsh B, Mehta A, Badawy M, Morse R, Pop R, Tidwell J, Sheehan M, McDermott S, Cannon C, Kahn J Pediatrics 2014 Feb
- Respiratory syncytial virus in neutrophils.
- Kahn JS J. Infect. Dis. 2012 Feb 205 4 693; author reply 693-4
- Seroepidemiology of WU polyomavirus among children exposed perinatally to HIV-1.
- Miller MA, Weibel C, Kahn JS, Andiman WA J. Med. Virol. 2012 Feb 84 2 188-93
- Induction of IL-6 and CCL5 (RANTES) in human respiratory epithelial (A549) cells by clinical isolates of respiratory syncytial virus is strain specific.
- Levitz R, Wattier R, Phillips P, Solomon A, Lawler J, Lazar I, Weibel C, Kahn JS Virol. J. 2012 9 190
- RNA interference-mediated silencing of the respiratory syncytial virus nucleocapsid defines a potent antiviral strategy.
- Alvarez R, Elbashir S, Borland T, Toudjarska I, Hadwiger P, John M, Roehl I, Morskaya SS, Martinello R, Kahn J, Van Ranst M, Tripp RA, DeVincenzo JP, Pandey R, Maier M, Nechev L, Manoharan M, Kotelianski V, Meyers R Antimicrob. Agents Chemother. 2009 Sep 53 9 3952-62
- WU polyomavirus in patients infected with HIV or hepatitis C virus, Connecticut, USA, 2007.
- Miller MA, Weibel C, Ferguson D, Landry ML, Kahn JS Emerging Infect. Dis. 2009 Jul 15 7 1095-7
- Rhinoviruses are a major cause of wheezing and hospitalization in children less than 2 years of age.
- Piotrowska Z, Vázquez M, Shapiro ED, Weibel C, Ferguson D, Landry ML, Kahn JS Pediatr. Infect. Dis. J. 2009 Jan 28 1 25-9
- Role of human polyomaviruses in respiratory tract disease in young children.
- Wattier RL, Vázquez M, Weibel C, Shapiro ED, Ferguson D, Landry ML, Kahn JS Emerging Infect. Dis. 2008 Nov 14 11 1766-8
- Seroepidemiology of human bocavirus defined using recombinant virus-like particles.
- Kahn JS, Kesebir D, Cotmore SF, D'Abramo A, Cosby C, Weibel C, Tattersall P J. Infect. Dis. 2008 Jul 198 1 41-50
Human Bocavirus: A Newly Discovered Human Parvovirus. In Scheld WM, Hooper DC, Hughes JM, eds. Emerging Infections 8.
Kahn JS, Tattersall P. (2008). Washington, DC:ASM Press; 21-38.
Honors & Awards
- Best Pediatric Specialists, D Magazine
- Pediatric Chair’s Award, Yale University School of Medicine
- Mae Gailani Junior Faculty Award, Yale University School of Medicine
- Infectious Diseases Society of America (2010)
- American Society of Virology (2002)
- American Society of Microbiology (2001)
- Society of Pediatric Research (2001)
- American Academy of Pediatrics