Featured Publications
Selective inhibition of hypoxia-inducible factor 1a ameliorates adipose tissue dysfunction.
Sun K, Halberg N, Khan M, Magalang UJ, Scherer PE Mol. Cell. Biol. 2013 Mar 33 5 904-17
Dichotomous effects of VEGF-A on adipose tissue dysfunction.
Sun K, Wernstedt Asterholm I, Kusminski CM, Bueno AC, Wang ZV, Pollard JW, Brekken RA, Scherer PE Proc. Natl. Acad. Sci. U.S.A. 2012 Apr 109 15 5874-9
Adipose tissue remodeling and obesity.
Sun K, Kusminski CM, Scherer PE J. Clin. Invest. 2011 Jun 121 6 2094-101
A short Nur77-derived peptide converts Bcl-2 from a protector to a killer.
Kolluri SK, Zhu X, Zhou X, Lin B, Chen Y, Sun K, Tian X, Town J, Cao X, Lin F, Zhai D, Kitada S, Luciano F, O'Donnell E, Cao Y, He F, Lin J, Reed JC, Satterthwait AC, Zhang XK Cancer Cell 2008 Oct 14 4
Phosphorylation of a conserved serine in the deoxyribonucleic acid binding domain of nuclear receptors alters intracellular localization.
Sun K, Montana V, Chellappa K, Brelivet Y, Moras D, Maeda Y, Parpura V, Paschal BM, Sladek FM Mol. Endocrinol. 2007 Jun 21 6 1297-311
AMP-activated protein kinase is involved in endothelial NO synthase activation in response to shear stress.
Zhang Y, Lee TS, Kolb EM, Sun K, Lu X, Sladek FM, Kassab GS, Garland T, Shyy JY Arterioscler. Thromb. Vasc. Biol. 2006 Jun 26 6 1281-7
The PPAR?-FGF1 axis: an unexpected mediator of adipose tissue homeostasis.
Sun K, Scherer PE Cell Res. 2012 Oct 22 10 1416-8
MitoNEET-driven alterations in adipocyte mitochondrial activity reveal a crucial adaptive process that preserves insulin sensitivity in obesity.
Kusminski CM, Holland WL, Sun K, Park J, Spurgin SB, Lin Y, Askew GR, Simcox JA, McClain DA, Li C, Scherer PE Nat. Med. 2012 Oct 18 10 1539-49
Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis.
He C, Bassik MC, Moresi V, Sun K, Wei Y, Zou Z, An Z, Loh J, Fisher J, Sun Q, Korsmeyer S, Packer M, May HI, Hill JA, Virgin HW, Gilpin C, Xiao G, Bassel-Duby R, Scherer PE, Levine B Nature 2012 Jan 481 7382 511-5
Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin.
Holland WL, Miller RA, Wang ZV, Sun K, Barth BM, Bui HH, Davis KE, Bikman BT, Halberg N, Rutkowski JM, Wade MR, Tenorio VM, Kuo MS, Brozinick JT, Zhang BB, Birnbaum MJ, Summers SA, Scherer PE Nat. Med. 2011 Jan 17 1 55-63
