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Proteomics & Metabolomics Course (MB5096)






Top-down mass spectrometry pays homage to the chemistry of biology. Chemical reactions in eukaryotes are programmed in both time and space; however, external stimuli (environment and disease) continually highjack these processes. The goal of my lab's research is to develop next generation proteomics tools that rapidly quantify hard to predict chemistry on translated genes in the context of normal eukaryote physiology as well as pathobiology associated with Alzheimer's disease spectrum disorders, Multiple Sclerosis, and other central nervous system diseases.



While studying the dynamics of PTMs in various diseases students will be able to train on (or develop) the most advanced proteomics technologies available. This offers students an unparallel experience to probe disease mechanisms at system’s wide level and not just single proteins alone.   We take pride in that researchers in our lab are multi-disciplinary coming from diverse backgrounds including molecular biology, medicine, chemistry, engineering, and computer science. We also take pride in that the projects we are pursuing not only promote basic understanding of disease pathology but also have great potential in translating novel findings to the patient bedside.



University of Northern Iowa (1998), Chemistry
Graduate School
University of Illinois Urbana (2004)

Research Interest

  • Alzheimer's Disease
  • Autoimmune disorders
  • Gene Transcription & cancers
  • Mass Spectrometry & protein biochips
  • Multiple Sclerosis
  • Neurodegeneration
  • Neuroinflammation
  • Post-translational modifications
  • Proteoforms
  • Proteomics
  • Translational Proteomics


Featured Publications LegendFeatured Publications


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Honors & Awards

  • The Friends of the Alzheimer's Disease Center
    Alzheimer's Disease Research Award (2013-2014)
  • Bioengineering Graduate Training Award
  • Interface Chemistry/Biochemistry Award
  • Southwestern Undergraduate Research Award
  • Southwestern Undergraduate Research Award
  • John L. Roach Scholar in Biomedical Research
  • QP-Summer Undergraduate Research Award
  • Endowed Scholarship, University of Texas Southwestern Medical Center
  • Brain Research Institute Research Award
  • University of Chicago Department of Pathology Post-Doctoral Scholarship
  • Department of Analytical Chemistry Seminar Student Choice Award
  • Student Opportunities for Academic Research Award (SOAR)
  • Norwest Bank Student Research Award
  • Presidential Cooperative Award
  • Student Opportunities for Academic Research Award (SOAR)

Professional Associations/Affiliations

  • Graduate Program: Computational and Systems Biology (2014)
  • Department of Bioengineering; University of Texas at Dallas (2012)
  • Graduate Program: Biomedical Engineering (2012)
  • Biomedical Engineering Graduate Program (2011)
  • Human Proteome Organisation (HUPO) (2011)
  • Biological Chemistry Graduate Program (2008)
  • Graduate Program: Biological Chemistry (2008)
  • American Chemical Society (ACS)
  • American Society of Mass Spectrometry (ASMS)
  • University of Texas at Dallas, Division of Materials Science and Engineering, Natural Science Engineering Research Laboratory (NSERL)