Fangyu Peng, M.D., Ph.D., is a physician-scientist who practices clinical nuclear medicine, with research interest in PET translational imaging and cancer therapy.

Dr. Peng is conducting translational research of inherited and acquired copper metabolism disorders in Wilson's disease, Alzheimer's disease, and traumatic brain injury.

Dr. Peng is studying copper metabolism as a theranostic target for molecular imaging and cancer therapy.


Medical School
Jiangxi Medical College (1982)
Graduate School
University of South Florida (1994), Medical Microbiology & Immunology
Ball Memorial Hospital (1996), Hematopathology
SUNY Upstate Medical University (1998), Pathology
University of Connecticut Health Center (2000), Nuclear Medicine
Hartford Hospital (2002), Anatomic Pathology
Warren Grant Magnuson Clinical Center - NIH (2003), Nuclear Medicine

Research Interest

  • Metabolic imaging of copper metabolism imbalance in Wilson's disease, Alzheimer's disease, and traumatic brain injury
  • Targeting copper metabolism for molecular cancer imaging and therapy


Featured Publications LegendFeatured Publications

Alteration of Copper Fluxes in Brain Aging: A Longitudinal Study in Rodent Using 64CuCl2-PET/CT.
Peng F, Xie F, Muzik O Aging Dis 2018 Feb 9 1 109-118
Radiopharmaceuticals for Assessment of Altered Metabolism and Biometal Fluxes in Brain Aging and Alzheimer's Disease with Positron Emission Tomography.
Xie F, Peng F J. Alzheimers Dis. 2017 Jun
Age-dependent changes of cerebral copper metabolism in Atp7b (-/-) knockout mouse model of Wilson's disease by [(64)Cu]CuCl2-PET/CT.
Xie F, Xi Y, Pascual JM, Muzik O, Peng F Metab Brain Dis 2017 Jan
Molecular imaging and therapy targeting copper metabolism in hepatocellular carcinoma.
Wachsmann J, Peng F World J. Gastroenterol. 2016 Jan 22 1 221-31
Detection of Increased 64Cu uptake in Traumatic Brain Injury with 64CuCl2-PET/CT.
Peng F, Muzik O, Gatson J, Kernie S, Diaz-Arrastia R J. Nucl. Med. 2015 Jun
Reduced 64Cu Uptake and Tumor Growth Inhibition by Knockdown of Human Copper Transporter 1 in Xenograft Mouse Model of Prostate Cancer.
Cai H, Wu JS, Muzik O, Hsieh JT, Lee RJ, Peng F J. Nucl. Med. 2014 Mar

Honors & Awards

  • Chief Resident in Nuclear Medicine
    University of Connecticut Health Center (1999-2000)

Professional Associations/Affiliations

  • American Society of Neurochemistry (2017)
  • International Society to Advance Alzheimer’s Research and Treatment (2016)
  • International Society for Neurochemistry (2015)
  • American College of Nuclear Medicine (2014)
  • Society of Nuclear Medicine and Molecular Imaging (1998)