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Dr. Lakshmi Raman’s interest is in brain injury and the care of ECMO (extracorporeal membrane oxygenation) patients. She has concentrated her lab interest in the effect of chronic hypoxia on the brain to her clinical expertise in critical care medicine.

As the Medical Director of the ECMO program and the ICU liaison for trauma patients at Children’s Health, she has focused her interest in the development of the program and advancing the field through research in these areas. She has been involved in doing some prospective studies in patients on ECMO and a study comparing different concentrations of hypertonic saline in the management of intracranial hypertension in traumatic brain injury. She is also an active member in the Extracorporeal Life Support Organization helping with their educational goals.


Medical School
University of Madras Medical College (1989)
State University New York Downstate (1998), Pediatrics
State University New York Downstate (2001), Pediatrics
University of Minnesota Medical School (2004), Pediatric Critical Care Medicine

Specialty Areas

Clinical Interest

  • Brain Injury
  • Research Interest

    • ECMO
    • Near infrared spectroscopy
    • Traumatic brain injury


    Featured Publications LegendFeatured Publications

    Regional cerebral abnormalities measured by frequency-domain near-infrared spectroscopy in pediatric patients during extracorporeal membrane oxygenation.
    Tian F, Jenks C, Potter D, Miles D, Raman L ASAIO J. 2016 Dec
    Successful engraftment after hematopoietic stem cell transplantation with infusion of donor stem cells through the extracorporeal membrane oxygenation circuit.
    Anton-Martin P, Darnell-Bowens C, Aquino VM, Jones T, Raman L Indian J Crit Care Med 2016 Oct 20 10 617-619
    Year in Review 2015: Extracorporeal Membrane Oxygenation.
    Raman L, Dalton HJ Respir Care 2016 Jul 61 7 986-91
    Perinatal chronic hypoxia induces cortical inflammation, hypomyelination, and peripheral myelin-specific T cell autoreactivity.
    Ortega SB, Kong X, Venkataraman R, Savedra AM, Kernie SG, Stowe AM, Raman L J. Leukoc. Biol. 2015 Jun
    Erythropoietin-mediated neuroprotection in a pediatric mouse model of chronic hypoxia.
    Chung E, Kong X, Goldberg MP, Stowe AM, Raman L Neurosci. Lett. 2015 Apr 597 54-59
    Assessments of cerebral blood flow, hemodynamics and metabolism in patients on ECMO using TCD and NIRS
    Tian F, Raman L, Golla S, Liu H. Biomedical Optics 2014 Apr
    Pharmacological inhibition of the mTOR pathway impairs hippocampal development in mice.
    Raman L, Kong X, Kernie SG Neurosci. Lett. 2013 Feb
    The use of extracorporeal life support in adolescent amlodipine overdose.
    Persad EA, Raman L, Thompson MT, Sheeran PW Indian J Crit Care Med 2012 Oct 16 4 204-6
    Chronic hypoxia impairs murine hippocampal development and depletes the postnatal progenitor pool by attenuating Mammalian target of rapamycin signaling.
    Raman L, Kong X, Gilley JA, Kernie SG Pediatr. Res. 2011 Aug 70 2 159-65
    Effects of chronic hypoxia in developing rats on dendritic morphology of the CA1 subarea of the hippocampus and on fear-potentiated startle.
    Raman L, Hamilton KL, Gewirtz JC, Rao R Brain Res. 2008 Jan 1190 167-74

    Honors & Awards

    • Center of Excellence with special recognition of the ECMO team
      Extracorporeal Life Support Organization (ELSO) (2014)
    • Press Ganey Award for Outstanding Patient Care
      Children's Medical Center (2011)
    • Principal Investigator
      Minneapolis Medical Research Foundation (2007)
    • Principal Investigator
      Vikings Children’s Fund-Grand in aid (2004)
    • Co-investigator
      Center for Neurobehavioral Development Research Grant (2002)
    • Jay H. Fisher Memorial Award for excellence in teaching
      SUNY, Brooklyn (2001)
    • Sixth Annual Residents Night Award
      Academy of Medicine of Richmond, NY (2001)
    • Distinction in Surgery
      Universtiy of Madras (1988)
    • Distinction in Anatomy and Biochemistry
      Universtiy of Madras (1984)

    Professional Associations/Affiliations

    • Extracorporeal Life Support Organization (2013)
    • Society of Pediatric Research (2008)
    • American Academy of Pediatrics (2000)