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Lakshmi Raman, M.D.

Lakshmi Raman, M.D.

Titles and Appointments

Professor

Schools
Medical School
Departments
Pediatrics

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For more information on the doctor and patient care, please visit the clinical profile.

  • Biography

    Download Curriculum Vitae

    Dr. Lakshmi Raman serves as the Medical Director of the Extracorporeal Membrane Oxygenation (ECMO) program She has primarily focused her efforts on education and research apart from overseeing the clinical care of these patients.

    Since ECMO is high-risk therapy with low probability events education is an integral part of running an ECMO program. We run a two day education course with hands on simulation for incoming fellows and specialists who assist in caring for the ECMO pump on a yearly basis and I oversee the curriculum. I also direct a 3-day National ECMO course once a year which has been endorsed by the Extra Corporeal Life Support Organization (ELSO) which is a parent organization and serve as the first course to be endorsed by ELSO and attended by participants across the Nation and Internationally.

    My research focus has been to evaluate the neurological injury in patients who are on Extracorporeal life support, otherwise commonly referred to as Extracorporeal Membrane Oxygenation (ECMO). I have collaborated this work with biomedical engineers and scientists in the lab. I previously had funding through AHA association and recently funded through the Hartwell Foundation to carry on this work through my collaborators. I am also working with the bioinformatics group at UT to use machine learning help understand neurological injuries. This work is primarily done by critical care fellows and have been awarded the Lyda-Hill Award to do the study. With my role as the Medical Director of the ECMO program at Children’s Medical Center of Dallas I am interested in finding ways to predict neurological events on ECMO.

    With my leadership and focus on ECMO, I have recently published my work that I have done both locally and nationally with ELSO community. I continue to present my work at National and International meetings.

    I also serve as a reviewer for Neuroscience Letters, Journal of Pediatric Surgical Research, ASAIO and serve on the review committee for fellow clinical grants and abstracts with Pediatric Academic Society. I also serve on the editorial board for ASAIO. I have been appointed to the steering committee at ELSO to chair the protocols, guidelines and grant committee. I also serve on the National committee for education and scientific review with ELSO data registry.

  • Education
    Medical School
    University of Madras Medical College (1989)
    Internship
    State University New York Downstate (1998), Pediatrics
    Residency
    State University New York Downstate (2001), Pediatrics
    Fellowship
    University of Minnesota Medical School (2004), Pediatric Critical Care Medicine
  • Research Interest
    • ECMO
    • Near infrared spectroscopy
    • Traumatic brain injury
  • Publications
    Early Electroencephalogram to Predict Severity of Injury in Infants With Abusive Traumatic Brain Injury
    Varughese NA, Hasan A, Cohen N, Smith D, Clarke RL, Grapsy J, Said R, Miles D, Raman L, Sirsi D Journal of child neurology 2026 May 41 704-714
    The association between early arterial oxygen and carbon dioxide with neurologic outcomes after pediatric ECPR in children with cardiac disease
    Yu P, Foster S, Zeida Haar L, Li X, Bhaskar P, Morriss M, Singh S, Burr T, Sirsi D, Raman L, Reeder R, Lasa JJ Resuscitation 2026 May 222
    Disruption of Cerebral Autoregulation Prior to Extracorporeal Membrane Oxygenation Cannulation Contributes to Neurologic Injury in Pediatric Patients
    Custer C, Ineza S, Liu H, Singh S, Morriss M, Tabet M, Busch D, Raman L, Sanford E Journal of Pediatric Research 2026 Mar 13 31-39
    Death by Neurologic Criteria in Neonates Undergoing Extracorporeal Membrane Oxygenation: Extracorporeal Life Support Organization Registry Study, 2010–2023
    Author Collaboration ob, Polito A, Gavotto A, Guerguerian AM, Bembea MM, Lorusso R, Hoskote A, Joram N, Zaaqoq AM, Cho SM, Di Nardo M, Raman L, Thiagarajan RR, Cvetkovic M, Shah N, Sanford E Pediatric Critical Care Medicine 2026 Mar 27 297-306
    EHR Sampling Interval Bias Detection and Burden of Blood Pressure Excursions: Implications for Clinical Decision Support and Model Validity in Pediatric ECMO
    Shah N, Sanford E, Busch DR, Singh R, Mathur S, Sharma J, Reeder P, Natarajan S, Raman L Information (Switzerland) 2026 Feb 17
    18: Pediatric Oncologic Patients with Anterior Mediastinal Masses on Extracorporeal Membrane Oxygenation: A Sub-analysis of Outcomes from a Multicenter, Retrospective Cohort Study, 2009-2021
    Chung N, Nelin S, Ontaneda A, Thomas J, Colin Mowrer M, Ghafoor S, Nair R, Reschke A, Raman L, Bhar S ASAIO Journal 2025 Oct 71 66
    Can we reduce the risk of neurological injury in critically ill children on initiation of ECLS? A narrative review of potential modifiable factors
    Author Collaboration Ob, Joram N, Thiagarajan RR, Bembea M, Cho SM, Guerguerian AM, Lorusso R, Polito A, Raman L, Sanford E, Shah N, Zaaqoq A, Hoskote A, Di Nardo M Perfusion (United Kingdom) 2025 Apr 40 29-38
    Prospective Randomized Pilot Study Comparing Bivalirudin Versus Heparin in Neonatal and Pediatric Extracorporeal Membrane Oxygenation
    McMichael A, Weller J, Li X, Hatton L, Zia A, Raman L Pediatric Critical Care Medicine 2025 Jan 26 e86-e94
    Extracorporeal membrane oxygenation in children with mediastinal masses from malignancy: A multicenter sub-analysis
    Chung N, Nelin S, Ontaneda A, Thomas J, Mowrer MC, Ghafoor S, Nair R, Reschke A, Raman L, Bhar S Perfusion (United Kingdom) 2025
    LLM-Guided Causal Bayesian Network Construction for Pediatric Patients on ECMO
    Mathur S, Singh R, Skinner M, Sanford E, Shah N, Reeder P, Raman L, Natarajan S 2025 255-260
  • Honors & Awards
    • Center of Excellence with special recognition of the ECMO team
      Extracorporeal Life Support Organization (ELSO) (2014)
    • Press Ganey Award for Outstanding Patient Care
      Children's Medical Center (2011)
    • Principal Investigator
      Minneapolis Medical Research Foundation (2007)
    • Principal Investigator
      Vikings Children’s Fund-Grand in aid (2004)
    • Co-investigator
      Center for Neurobehavioral Development Research Grant (2002)
    • Jay H. Fisher Memorial Award for excellence in teaching
      SUNY, Brooklyn (2001)
    • Sixth Annual Residents Night Award
      Academy of Medicine of Richmond, NY (2001)
    • Distinction in Surgery
      Universtiy of Madras (1988)
    • Distinction in Anatomy and Biochemistry
      Universtiy of Madras (1984)
  • Professional Associations/Affiliations
    • American Academy of Pediatrics (2000)
    • Extracorporeal Life Support Organization (2013)
    • Society of Pediatric Research (2008)