Biography

Dr. Aquino clinical interest focus on pediatric bone marrow transplantation. He is active in the Pediatric Blood and Marrow Transplant Consortium. He has served as PI on several research protocols, is a member of the Data Safety Management Committee of several protocols, and is a member of the Oncology and Supportive Care Subcommittees of the group. He is also collaborating as institutional PI on several studies in non-myeloablative transplant and unrelated umbilical cord blood transplant. His other research interests have focused on the prevention and management of infection in children with cancer receiving chemotherapy and those who undergo hematopoietic stem cell transplant. He has performed research in immune reconstitution, management of infections, and developed protocols for outpatient management of febrile neutropenia. He is also an active member of the Children's Oncology Group and has served as a PI of a multi-institutional phase I study for the group. He is currently the co-director of the contract COG Phase I center and is a member of the Developmental Therapeutics Committee.

Education

Medical School
State University of New York - Syracuse (1989)
Residency
State University of New York - Syracuse (1992), Pediatrics
Fellowship
UT Southwestern - Children's Medical Center (1995), Pediatric Hematology/oncology

Specialty Areas

Clinical Interest

  • Stem Cell Transplantation
  • Research Interest

    • Development of stem cell transplant protocols for children with malignant and non-malignant disorders.
    • Development of treatment strategies to manage the complications of stem cell transplant and chemotherapy.
    • Management of bacterial and fungal infections in children with malignancies.
    • Outpatient management of febrile neutropenia in selected patients with cancer.
    • Phase I and II trials of new chemotherapeutic agents in children with cancer.

    Publications

    Featured Publications LegendFeatured Publications

    Safety, pharmacokinetics and efficacy of palifermin in children and adolescents with acute leukemias undergoing myeloablative therapy and allogeneic hematopoietic stem cell transplantation: a Pediatric Blood and Marrow Transplant Consortium Trial.
    Morris J, Rudebeck M, Neudorf S, Moore T, Duerst R, Shah AJ, Graham M, Aquino V, Morris C, Olsson B Biol. Blood Marrow Transplant. 2016 Mar
    Incidence and outcome of rhinovirus in children undergoing hematopoietic stem cell transplantation.
    DeMasi J, Aquino V, Simms-Waldrip TR, Koh AY, Holmes S. Biology of Blood and Marrow Transplantation 2015 15 2 S248
    One-unit versus two-unit cord-blood transplantation for hematologic cancers.
    Wagner JE, Eapen M, Carter S, Wang Y, Schultz KR, Wall DA, Bunin N, Delaney C, Haut P, Margolis D, Peres E, Verneris MR, Walters M, Horowitz MM, Kurtzberg J N. Engl. J. Med. 2014 Oct 371 18 1685-94
    Transplantation outcomes for severe combined immunodeficiency, 2000-2009.
    Pai SY, Logan BR, Griffith LM, Buckley RH, Parrott RE, Dvorak CC, Kapoor N, Hanson IC, Filipovich AH, Jyonouchi S, Sullivan KE, Small TN, Burroughs L, Skoda-Smith S, Haight AE, Grizzle A, Pulsipher MA, Chan KW, Fuleihan RL, Haddad E, Loechelt B, Aquino VM, Gillio A, Davis J, Knutsen A, Smith AR, Moore TB, Schroeder ML, Goldman FD, Connelly JA, Porteus MH, Xiang Q, Shearer WT, Fleisher TA, Kohn DB, Puck JM, Notarangelo LD, Cowan MJ, O'Reilly RJ N. Engl. J. Med. 2014 Jul 371 5 434-46
    Intravenous Pentamidine Is Safe and Effective as Primary Pneumocystis Pneumonia Prophylaxis in Children and Adolescents Undergoing Hematopoietic Stem Cell Transplantation.
    Demasi JM, Cox JA, Leonard D, Koh AY, Aquino VM Pediatr. Infect. Dis. J. 2013 Mar

    Professional Associations/Affiliations

    • Society of Pediatric Research (2002)
    • American Society of Hematology (1997)
    • American Society of Clinical Oncology (1996)
    • Dallas County Medical Society and Texas Medical Association (1996)
    • American Academy of Pediatrics (1989)
    • Children's Oncology Group