Victor Aquino, M.D.
Associate Professor
Department: Pediatrics
Biography
Dr. Aquino clinical interest focus on pediatric bone marrow transplantation. He is active in the Pediatric Blood and Marrow Transplant Consortium. He has served as PI on several research protocols, is a member of the Data Safety Management Committee of several protocols, and is a member of the Oncology and Supportive Care Subcommittees of the group. He is also collaborating as institutional PI on several studies in non-myeloablative transplant and unrelated umbilical cord blood transplant. His other research interests have focused on the prevention and management of infection in children with cancer receiving chemotherapy and those who undergo hematopoietic stem cell transplant. He has performed research in immune reconstitution, management of infections, and developed protocols for outpatient management of febrile neutropenia. He is also an active member of the Children's Oncology Group and has served as a PI of a multi-institutional phase I study for the group. He is currently the co-director of the contract COG Phase I center and is a member of the Developmental Therapeutics Committee.
Education
| Medical School | State Univerisity of New York - Syracuse (1989) |
| Residency | State University of New York - Syracuse (1992), Pediatrics |
| Fellowship | UT Southwestern / Children's Medical Center (1995), Pediatric Hematology/oncology |
Specialty Areas
Clinical Interests
- Primary Interests
- Stem Cell Transplantation
Research Interests
- Development of stem cell transplant protocols for children with malignant and non-malignant disorders.
- Development of treatment strategies to manage the complications of stem cell transplant and chemotherapy.
- Management of bacterial and fungal infections in children with malignancies.
- Outpatient management of febrile neutropenia in selected patients with cancer.
- Phase I and II trials of new chemotherapeutic agents in children with cancer.
Publications
Featured Publications
Oral ciprofloxacin in the outpatient management of children with cancer with febril neutropenia at low risk of bacteremia.
Aquino VM, Herrera L, Sandler ES, Buchanan GR Cancer 2000 88 1710-1714
Evaluation of thymic output by measurment of T-cell-receptor gene rearrangement excisional circles (TREC) in patients who have received fludarabine
Aquino VM, Douek DC, Berryman B, Johnson M, Jain V, Collins RH Leukemia and Lymphoma 2003 44 343-348
A prospective double blind randomized trial of urokinase flushes to prevent bacteremia due to luminal colonization of central venous catheters.
Aquino VM, Sandler ES, Mustafa MM, Steele J, Buchanan GR J Pediatr Hematol Oncol 2002 24 710-713
Clinical parameters associated with low bacteremia risk in 1100 pediatric oncology patients with fever and neutropenia
Baorto EP,Aquino VM, Mullen CA, Buchanan GR Cancer 2001 92 909-913
Oral ciprofloxacin in the outpatient management of children with cancer with febril neutropenia at low risk of bacteremia.
Aquino VM, Herrera L, Sandler ES, Buchanan GR Cancer 2000 88 1710-1714
A phase II study of carboplatin in the treatment of low grade optic gliomas.
Aquino VM, Fort D, Kamen B Journal of Neuro-Oncology 1999 41 255-259
The use of supplemental glutamine to decrease morbidity in children undergoing stem cell transplantation: A Pediatric Blood and Marrow Transplant Consortium Study.
Aquino VM, Harvey A, Garvin JH, Godder K, Nieder ML, Adams RH, Jackson GB, Sandler ES for the Pediatric Blood and Marrow Transplant Corsortium Bone Marrow Transplant 2005 36 611-616
Phase I study of oral cyclophosphamide and oral topotecan for children with recurrent and refractory solid tumors.
Bowers DC, Aquino VM, Leavey PJ, Bash RO, Journeycake JM, Tomlinson G, Mulne AF, and Winick NJ Pediatr Blood Cancer 2004 42 93-98
Phase I study of tirapazamine and cyclophosphamide in childrenwith refractor solid tumors.
Aquino VM, Weitman SD, Winick NJ, Blaney S, Furman WL, Kepner JL, Krailo M, Qu W, Bernstein M J Clin Oncol 2004 22 1413-1419
Unusual immunophenotype of CD8+ T-cells in familial hemphagocytic lymphohistiocytosis.
Karandikar NJ, Kroft SH, Yegappan S, Rogers BB, Aquino VM, Lee K, Kumar V, Guenaga FJ, Jaffe ES, Douek DC, McKenna RW Blood 2004 104 2007-2009
Professional Associations/Affiliations
- American Society of Clinical Oncology
- American Society of Hematology
- Childrens Oncolgy Group
- Dallas County Medical Society and Texas Medical Association
- Society of Pediatric Research