Dr. Aquino clinical interest focus on pediatric bone marrow transplantation. He is active in the Pediatric Blood and Marrow Transplant Consortium. He has served as PI on several research protocols, is a member of the Data Safety Management Committee of several protocols, and is a member of the Oncology and Supportive Care Subcommittees of the group. He is also collaborating as institutional PI on several studies in non-myeloablative transplant and unrelated umbilical cord blood transplant. His other research interests have focused on the prevention and management of infection in children with cancer receiving chemotherapy and those who undergo hematopoietic stem cell transplant. He has performed research in immune reconstitution, management of infections, and developed protocols for outpatient management of febrile neutropenia. He is also an active member of the Children's Oncology Group and has served as a PI of a multi-institutional phase I study for the group. He is currently the co-director of the contract COG Phase I center and is a member of the Developmental Therapeutics Committee.


Medical School
State University of New York - Syracuse (1989)
State University of New York - Syracuse (1992), Pediatrics
UT Southwestern - Children's Medical Center (1995), Pediatric Hematology/oncology

Specialty Areas

Clinical Interest

  • Stem Cell Transplantation
  • Research Interest

    • Development of stem cell transplant protocols for children with malignant and non-malignant disorders.
    • Development of treatment strategies to manage the complications of stem cell transplant and chemotherapy.
    • Management of bacterial and fungal infections in children with malignancies.
    • Outpatient management of febrile neutropenia in selected patients with cancer.
    • Phase I and II trials of new chemotherapeutic agents in children with cancer.


    Featured Publications LegendFeatured Publications

    The use of supplemental glutamine to decrease morbidity in children undergoing stem cell transplantation: A Pediatric Blood and Marrow Transplant Consortium Study.
    Aquino VM, Harvey A, Garvin JH, Godder K, Nieder ML, Adams RH, Jackson GB, Sandler ES for the Pediatric Blood and Marrow Transplant Corsortium Bone Marrow Transplant 2005 36 611-616
    Phase I study of oral cyclophosphamide and oral topotecan for children with recurrent and refractory solid tumors.
    Bowers DC, Aquino VM, Leavey PJ, Bash RO, Journeycake JM, Tomlinson G, Mulne AF, and Winick NJ Pediatr Blood Cancer 2004 42 93-98
    Phase I study of tirapazamine and cyclophosphamide in childrenwith refractor solid tumors.
    Aquino VM, Weitman SD, Winick NJ, Blaney S, Furman WL, Kepner JL, Krailo M, Qu W, Bernstein M J Clin Oncol 2004 22 1413-1419
    Unusual immunophenotype of CD8+ T-cells in familial hemphagocytic lymphohistiocytosis.
    Karandikar NJ, Kroft SH, Yegappan S, Rogers BB, Aquino VM, Lee K, Kumar V, Guenaga FJ, Jaffe ES, Douek DC, McKenna RW Blood 2004 104 2007-2009

    Professional Associations/Affiliations

    • American Society of Clinical Oncology
    • American Society of Hematology
    • Children's Oncology Group
    • Dallas County Medical Society and Texas Medical Association
    • Society of Pediatric Research