Xiaorong Fu, Ph.D. Associate Professor School Medical School Department Center for Human Nutrition | Internal Medicine Graduate Programs Biological Chemistry Education Undergraduate (1992), Chemistry Graduate School (2001), Chemistry Graduate School Tufts University (2005), Chemistry Research Interest Flux analysis High-resolution mass spectrometry LC-mass spectrometry based metabolomics Stable isotope tracers Publications Featured Publications In Vivo Estimation of Ketogenesis Using Metabolic Flux Analysis-Technical Aspects and Model Interpretation. Deja S, Kucejova B, Fu X, Browning JD, Young JD, Burgess S, Metabolites 2021 Apr 11 5 Measurement of lipogenic flux by deuterium resolved mass spectrometry Xiaorong Fu, Stanislaw Deja, Justin A Fletcher, Norma N Anderson, Monika Mizerska, Gonçalo Vale, Jeffrey D Browning, Jay D Horton, Jeffrey G McDonald, Matthew A Mitsche, Shawn C Burgess Nat Commun 2021 1 12 3756 In Vivo Estimation of Ketogenesis Using Metabolic Flux Analysis-Technical Aspects and Model Interpretation Deja S, Kucejova B, Fu X, Browning JD, Young JD, Burgess S Metabolites 2021 11(5) 28 279 Hepatic deletion of Mboat7 (LPIAT1) causes activation of SREBP-1c and fatty liver Xia M, Chandrasekaran P, Rong S, Fu X, Mitsche MA J Lipid Res 2021 62 100031 Impaired ketogenesis and increased acetyl-CoA oxidation promote hyperglycemia in human fatty liver. Fletcher JA, Deja S, Satapati S, Fu X, Burgess SC, Browning JD, JCI Insight 2019 Apr 5 Pyruvate-Carboxylase-Mediated Anaplerosis Promotes Antioxidant Capacity by Sustaining TCA Cycle and Redox Metabolism in Liver. Cappel DA, Deja S, Duarte JAG, Kucejova B, Iñigo M, Fletcher JA, Fu X, Berglund ED, Liu T, Elmquist JK, Hammer S, Mishra P, Browning JD, Burgess SC, Cell Metab. 2019 Apr Targeted Determination of Tissue Energy Status by LC-MS/MS. Fu X, Deja S, Kucejova B, Duarte JAG, McDonald JG, Burgess SC, Anal. Chem. 2019 Apr The mitochondrial pyruvate carrier mediates high fat diet-induced increases in hepatic TCA cycle capacity. Rauckhorst AJ, Gray LR, Sheldon RD, Fu X, Pewa AD, Feddersen CR, Dupuy AJ, Gibson-Corley KN, Cox JE, Burgess SC, Taylor EB Mol Metab 2017 Nov 6 11 1468-1479 FGF19, FGF21, and an FGFR1/?-Klotho-Activating Antibody Act on the Nervous System to Regulate Body Weight and Glycemia. Lan T, Morgan DA, Rahmouni K, Sonoda J, Fu X, Burgess SC, Holland WL, Kliewer SA, Mangelsdorf DJ Cell Metab. 2017 Oct Acetyl CoA Carboxylase Inhibition Reduces Hepatic Steatosis but Elevates Plasma Triglycerides in Mice and Humans: A Bedside to Bench Investigation. Kim CW, Addy C, Kusunoki J, Anderson NN, Deja S, Fu X, Burgess SC, Li C, Ruddy M, Chakravarthy M, Previs S, Milstein S, Fitzgerald K, Kelley DE, Horton JD Cell Metab. 2017 Aug 26 2 394-406.e6 Results 1-10 of 12 1 2 Next Last Professional Associations/Affiliations The American Society for Mass Spectrometry (2019)
