Janine Prange-Kiel, Ph.D.
Assistant Professor

Graduate School

University of Tuebingen , Cell Biology

• Effects of estradiol and synaptic plasticity
• Regulation of hippocampal estradiol synthesis
• Steroids in the brain

Featured Publications

Gonadotropin-releasing hormone regulates spine density via its regulatory role in hippocampal estrogen synthesis.

Prange-Kiel J, Jarry H, Schoen M, Kohlmann P, Lohse C, Zhou L, Rune GM. Journal of Cell Biology February 2008 180/2 417-26

Inhibition of hippocampal estrogen synthesis causes region-specific downregulation of synaptic protein expression in hippocampal neurons.

Prange-Kiel J, Fester L, Zhou L, Lauke H, Carretero J, Rune GM. Hippocampus 2006 16/5 464-71

Hippocampal synapses depend on hippocampal estrogen synthesis.

Kretz O, Fester L, Wehrenberg U, Zhou L, Brauckmann S, Zhao S, Prange-Kiel J, Naumann T, Jarry H, Frotscher M, Rune GM. Journal of Neuroscience June 2004 24/26 5913-21

Median raphe mediates estrogenic effects to the hippocampus in female rats.

Prange-Kiel J, Rune GM, Leranth C. European Journal of Neuroscience January 2004 19/2 309-17

Para/autocrine regulation of estrogen receptors in hippocampal neurons.

Prange-Kiel J, Wehrenberg U, Jarry H, Rune GM. Hippocampus 2003 13/2 226-34

Role of tumor necrosis factor in preovulatory follicles of swine.

Prange-Kiel J, Kreutzkamm C, Wehrenberg U, Rune GM. Biology of reproduction September 2001 65/3 928-35

Role of tumor necrosis factor in preovulatory follicles of swine.

Prange-Kiel J, Kreutzkamm C, Wehrenberg U, Rune GM. Biology of reproduction September 2001 65/3 928-35

Gonadotropin-releasing hormone regulates spine density via its regulatory role in hippocampal estradiol synthesis

Prange-Kiel J, Jarry H, Schoen M, Kohlmann P, Lohse C, Zhou L, Rune GM Journal of Cell Biology January 2008 180/2 417-26

Oestrogen synthesis in the hippocampus: role in axon outgrowth

von Schassen C, Fester L, Prange-Kiel J, Lohse C, Huber C, Boettner M, Rune GM Journal of Neuroendocrinology November 2006 18/11 847-56

Proliferation and apoptosis of hippocampal granule cells require local oestrogen synthesis.

Fester L, Ribeiro-Gouveia V, Prange-Kiel J, von Schassen C, Bottner M, Jarry H, Rune GM Journal of Neurochemistry May 2006 97/4 1136-44

• Alzheimer’s Disease Research Award
  Pilot grant by the Friends of the Alzheimer’s Disease Center (2009)
• Fellowship of the German Research Foundation
  (2002)

• Anatomische Gesellschaft
• Endocrine Society
• Neurowissenschaftliche Gesellschaft
• Society for Neuroscience