Janine Prange-Kiel, Ph.D. Associate Professor School Medical School Department Surgery Graduate Programs Neuroscience Education Graduate School University of Tuebingen , Cell Biology Research Interest Effects of estradiol and synaptic plasticity Progranulin deficiency-related dementia Regulation of hippocampal estradiol synthesis Steroids in the brain Publications Featured Publications Lipidomic and Transcriptomic Basis of Lysosomal Dysfunction in Progranulin Deficiency. Evers BM, Rodriguez-Navas C, Tesla RJ, Prange-Kiel J, Wasser CR, Yoo KS, McDonald J, Cenik B, Ravenscroft TA, Plattner F, Rademakers R, Yu G, White CL, Herz J Cell Rep 2017 Sep 20 11 2565-2574 Embryology, Anatomy, and Radiology of Cervical Cysts and Cleft Lip/Palate: A Team-Based Learning Module for Medical Students. Prange-Kiel J, Champine JG, Winkler AJ, Twickler DM, MedEdPORTAL 2016 Oct 12 10484 Inhibition of hippocampal estrogen synthesis causes region-specific downregulation of synaptic protein expression in hippocampal neurons. Prange-Kiel J, Fester L, Zhou L, Lauke H, Carretero J, Rune GM. Hippocampus 2006 16/5 464-71 Hippocampal synapses depend on hippocampal estrogen synthesis. Kretz O, Fester L, Wehrenberg U, Zhou L, Brauckmann S, Zhao S, Prange-Kiel J, Naumann T, Jarry H, Frotscher M, Rune GM. Journal of Neuroscience June 2004 24/26 5913-21 Median raphe mediates estrogenic effects to the hippocampus in female rats. Prange-Kiel J, Rune GM, Leranth C. European Journal of Neuroscience January 2004 19/2 309-17 Para/autocrine regulation of estrogen receptors in hippocampal neurons. Prange-Kiel J, Wehrenberg U, Jarry H, Rune GM. Hippocampus 2003 13/2 226-34 Role of tumor necrosis factor in preovulatory follicles of swine. Prange-Kiel J, Kreutzkamm C, Wehrenberg U, Rune GM. Biology of reproduction September 2001 65/3 928-35 Aromatase Expression in the Hippocampus of AD Patients and 5xFAD Mice. Prange-Kiel J, Dudzinski DA, Pröls F, Glatzel M, Matschke J, Rune GM Neural Plast. 2016 2016 9802086 Endocrine regulation of estrogen synthesis in the hippocampus? Prange-Kiel J, Schmutterer T, Fester L, Zhou L, Imholz P, Brandt N, Vierk R, Jarry H, Rune GM Prog Histochem Cytochem 2013 Aug 48 2 49-64 Estrogen-regulated synaptogenesis in the hippocampus: sexual dimorphism in vivo but not in vitro. Fester L, Prange-Kiel J, Zhou L, Blittersdorf BV, Böhm J, Jarry H, Schumacher M, Rune GM J. Steroid Biochem. Mol. Biol. 2012 Aug 131 1-2 24-9 Results 1-10 of 31 1 2 3 4 Next Last Books Featured Books Embryology of the Head and Neck. In Atlas of Oral & Maxillofacial Surgery Kademani D, Tiwana P (Ed.) (2016). St. Louis, MO, USA, Elsevier Zur zerebralen Wirkung von Östrogenen (Cerebral effects of estrogens). In Intersexualität Kontrovers Schweizer K, Richter-Appelt H (Ed.) (2012). Psychosozial-Verlag Auto- und parakrine Regulation im ZNS: Neurosteroide (Autocrine and paracrine regulation in the CNS, Neurosteroids). In Molekularmedizinische Grundlagen von Endokrinopathien 2- Para- und autokrine Regulation Ganten D, Ruckpaul K (Ed.) (2006). Thieme Illustrated Handbook of Succulent Plants: Asclepiadaceae Albers F, Meve U (Ed.) (2004). Berlin, Germany, Springer Verlag Honors & Awards UT Southwestern Academy of Teachers [SWAT], Elected Member (2019) UT Southwestern Academy of Teachers [SWAT], Small Grant AwardProject title: Effects of The Origami Embryo, a hands-on exercise, on the understanding of early embryonic development (2019) Alzheimer’s Disease Research AwardPilot grant by the Friends of the Alzheimer’s Disease Center (2009) Professional Associations/Affiliations American Association for Anatomy (2016) Anatomische Gesellschaft (2000) Neurowissenschaftliche Gesellschaft (2004) Society for Neuroscience (2004)