Anil Agarwal, Ph.D. - Faculty Profile

Biography

Anil Agarwal, Ph.D., is a Professor in the Department of Internal Medicine at UT Southwestern Medical Center and a member of the Division of Endocrinology.

Originally from India, Dr. Agarwal holds a bachelor's degree in zoology, chemistry, and botany and a master's degree in biochemistry from the University of Allahabad. He earned his doctorate in biochemistry and chemistry at Kanpur University. He completed a research fellowship in endocrinology at the Central Drug Research Institute in India and completed a postdoctoral fellowship in endocrinology at the Rockefeller University in New York.

Dr. Agarwal joined the UT Southwestern faculty as a Research Instructor in the Department of Pediatrics in 1994. He was promoted to Assistant Professor of Internal Medicine in 2001, Associate Professor in 2004, and Professor in 2012.

Dr. Agarwal is a member of the Endocrine Society and the American Society for Biochemistry and Molecular Biology.

Education

Graduate School: Kanpur University (1982)

Research Interest

Functional aspects of acyltransferases
Molecular aspects of lipodystrophy
Molecular aspects of premature aging

Publications

Gain of Function NOTCH3 Variants Cause Familial Partial Lipodystrophy Due to Activation of Senescence Pathways: Garg A, Xing C, Agarwal AK, Westfall AK, Tomchick DR, Zhang X, Xing M, Brown RJ Diabetes 2025 Mar 74 427-438
Regulated regeneration of adipose tissue in lipodystrophic Agpat2-null mice partially ameliorates hepatic steatosis: Agarwal AK, Tunison K, Horton JD, Garg A iScience 2024 Apr 27
Phospholipid biosynthetic pathways and lipodystrophies: a novel syndrome due to PLAAT3 deficiency: Agarwal AK, Garg A Nature Reviews Endocrinology 2024 Mar 20 128-129
Adipose-specific overexpression of human AGPAT2 in mice causes increased adiposity and mild hepatic dysfunction: Agarwal AK, Tunison K, Vale G, McDonald JG, Li X, Horton JD, Garg A iScience 2024 Jan 27
Early-onset diabetes mellitus as a presenting feature of Werner's syndrome in an Indian family: Hoff FW, Xing C, Simha V, Agarwal AK, Zhang X, Lekkala L, Vaishnav MS, Vuitch F, Garg A Molecular Genetics and Genomic Medicine 2024 Jan 12
Diffusion-weighted imaging of the orbit: Tejani AS, Berson E, Phillip J, Feltrin FS, Bazan C, Raj KM, Agarwal AK, Maldjian JA, Lee WC, Yu FF Clinical Radiology 2024 Jan 79 10-18
Regulated adipose tissue-specific expression of human AGPAT2 in lipodystrophic Agpat2-null mice results in regeneration of adipose tissue: Agarwal AK, Tunison K, Vale G, McDonald JG, Li X, Scherer PE, Horton JD, Garg A iScience 2023 Oct 26
Autoantibodies to Perilipin-1 Define a Subset of Acquired Generalized Lipodystrophy: Mandel-Brehm C, Vazquez SE, Liverman C, Cheng M, Quandt Z, Kung AF, Parent A, Miao B, Disse E, Cugnet-Anceau C, Dalle S, Orlova E, Frolova E, Alba D, Michels A, Oftedal BE, Lionakis MS, Husebye ES, Agarwal AK, Li X, Zhu C, Li Q, Oral E, Brown R, Anderson MS, Garg A, DeRisi JL Diabetes 2023 Jan 72 59-70
Autosomal recessive progeroid syndrome due to homozygosity for a TOMM7 variant: Garg A, Keng WT, Chen Z, Sathe AA, Xing C, Kailasam PD, Shao Y, Lesner NP, Llamas CB, Agarwal AK, Mishra P Journal of Clinical Investigation 2022 Dec 132
Face-sparing Congenital Generalized Lipodystrophy Type 1 Associated With Nonclassical Congenital Adrenal Hyperplasia: Costa S, Sampaio L, Berta Sousa A, Xing C, Agarwal AK, Garg A Journal of Clinical Endocrinology and Metabolism 2022 Sep 107 2433-2438

Honors & Awards

Chair
Succession on 'Recent Advances Through Animal Models' at the Lipodystrophy 2024 Consensus Symposium (2024)
Member, Editorial Board
Molecular Nutrition and Food Research (2007)
Member, Editorial Board
Journal of Clinical Endocrinology and Metabolism (2006)
Member, Reviewer Panel
American Journal of Physiology:Regulatory, Integrative, and Comparative Physiology (2006)
Abstract to the Endocrine Society
Honored for presentation as a Presidential Selection (1990)
CIBA Bursary
CIBA Foundation, UK (1984)

Professional Associations/Affiliations

The Endocrine Society