Chengcheng Zhang, Ph.D.

Associate Professor

Endowed Title: Michael L. Rosenberg Scholar in Medical Research

Department: Physiology, Developmental Biology

Graduate Programs: Immunology, Integrative Biology

Education

Undergraduate University of Science Technology - China (), Molecular Cell Biology
Graduate School "chinese Academy of Sciences, Shanghai, China" (1995)
Graduate School University of Illinois Urbana Campus (1999)

Research Interests

  • Ex vivo expansion of HSCs for cell therapy and gene therapy
  • Interplay between stem cells and cancer
  • Interplay between stem cells and immunity
  • Roles of ITIM-receptors in leukemia

Publications

Featured Publications Legend

Featured Publications

Hypoxia and Metabolic Properties of Hematopoietic Stem Cells. Antioxidants & Redox Signaling

Zhang CC, Sadek H. Antioxidants & Redox Signaling. 2014 12 20 epub

Profilin-1 is essential for retention and metabolism of mouse hematopoietic stem cells in bone marrow.

Zheng J, Lu Z, Kocabas F, Bottcher RT, Costell M, Kang X, Liu X, DeBerardinis RJ, Wang Q, Chen G, Sadek H*, Zhang CC*. Blood 2014 123 992-1001

Novel signaling axis in CML-initiating cells.

Zhang CC Blood 2014 16 123

A motif in LILRB2 critical for Angptl2 binding and activation

Deng M*, Lu Z*, Zheng J, Wan X, Chen X, Hirayasu K, Sun H, Lam Y, Chen L, Wang Q, Song C, Huang N, Gao GF, Jiang Y, Arase H, Zhang CC. Blood 2014 epub

Meis1 regulates the metabolic phenotype and oxidative defense of hematopoietic stem cells.

Kocabas F, Zheng J, Thet S, Copeland NG, Jenkins NA, DeBerardinis RJ, Zhang CC*, Sadek HA*. Blood 2012 25 120 4963-72

Results 1-10 of 13

Honors/Awards

  • Leukemia & Lymphoma Society Scholar Award
    (2013)
  • Royan International Research Award
    (2012)
  • Gabrielle’s Angel Foundation for Cancer Research Fellow
    (2009)
  • Basil O’Connor Scholar, March of Dimes Foundation
    (2008)
  • American Society of Hematology Junior Faculty Scholar
    (2007)
  • Howard Temin KO1 Award, National Cancer Institute
    (2006)
  • Michael L. Rosenberg Scholar in Biomedical Research, UT Southwestern Medical Center
    (2006)

Professional Associations/Affiliations

  • American Society for Cell Biology
  • American Society of Hematology
  • International Society for Stem Cell Research