Univ of Science & Tech China , Molecular & Cell Biology
Graduate School
Chinese Academy of Sciences-Sh (1995), Biotechnology
Graduate School
Univ of Illinois @ Urbana-Cham (1999), Biochemistry

Research Interest

  • Angiopoietin-like proteins and receptors
  • Cancer, immune checkpoints, stem cells
  • Roles of ITIM-receptors in cancer and immunity


Featured Publications LegendFeatured Publications

Hypoxia fate-mapping identifies cycling cardiomyocytes in the adult heart
Kimura W, Xiao F, Canseco DC, Muralidhar S, Thet S, Zhang HM, Abderrahman Y, Chen R, Garcia JA, Shelton JM, Richardson JA, Ashour AM, Asaithamby A, Liang H, Xing C, Lu Z, Zhang CC, Sadek HA. Nature 2015 7559 523 226-230
Hypoxia and Metabolic Properties of Hematopoietic Stem Cells. Antioxidants & Redox Signaling
Zhang CC, Sadek H. Antioxidants & Redox Signaling. 2014 12 20 epub
Profilin-1 is essential for retention and metabolism of mouse hematopoietic stem cells in bone marrow.
Zheng J, Lu Z, Kocabas F, Bottcher RT, Costell M, Kang X, Liu X, DeBerardinis RJ, Wang Q, Chen G, Sadek H*, Zhang CC*. Blood 2014 123 992-1001
Novel signaling axis in CML-initiating cells.
Zhang CC Blood 2014 16 123

Honors & Awards

  • Hortense L. and Morton H. Sanger Professorship in Oncology
  • Leukemia & Lymphoma Society Scholar Award
  • Royan International Research Award
  • Gabrielle’s Angel Foundation for Cancer Research Fellow
  • Basil O’Connor Scholar, March of Dimes Foundation
  • American Society of Hematology Junior Faculty Scholar
  • Howard Temin KO1 Award, National Cancer Institute
  • Michael L. Rosenberg Scholar in Biomedical Research, UT Southwestern Medical Center

Professional Associations/Affiliations

  • American Society for Cell Biology
  • American Society of Hematology
  • International Society for Stem Cell Research