Jin Jiang, Ph.D.

Professor

Endowed Title: Eugene McDermott Scholar in Medical Research

Department: Developmental Biology, Pharmacology

Graduate Programs: Cancer Biology

Education

Undergraduate Fudan University - China (1986)
Graduate School Columbia University in the City of New York (1992)

Research Interests

  • Cell signaling pathways important for animal development and human diseases.
  • Genes and pathways involved in cell growth, differentiation, and pattern
  • Hedgehog and Wnt signal transduction pathways.
  • Tumor suppressor genes and mechanism of oncogenesis.

Publications

Featured Publications Legend

Featured Publications

The TEAD/TEF family of transcription factor Scalloped mediates Hippo signaling in organ size control

Lei Zhang, Fangfang Ren, Qing Zhang, Yongbin Chen, Bing Wang, and Jin Jiang Developmental Cell March 2008 14 377-387

Hedgehog regulates Smoothened activity by inducing a conformational switch

Yun Zhao, Chao Tong, and Jin Jiang Nature (article) November 2007 450, 252-258

A Hedgehog-induced BTB protein modulates Hedgehog signaling responses by degrading Ci/Gli transcription factor

Qing Zhang, Lei Zhang, Bing Wang, Chan-Yen Ou, Cheng-Ting Chien, and Jin Jiang. Developmental Cell June 2006 10 719-729

Phosphorylation of Cubitus interruptus by Double-time/CKIbeta and CKIalpha targets it for Slimb/beta-TRCP mediated proteolytic processing

Jia, J., Ho, F., Tong, C., Zhang, Q., Wang, G., Wang, B., Amanai, K., and Jiang, J Dev. Cell 2005 9 819-830

Hedgehog Signalling Activity of Smoothened Requires Phosphorylation by Protein Kinase A and Casein Kinase I

Jianhang Jia, Chao Tong, Bing Wang, Liping Luo and Jin Jiang Nature 2004 432 1045-1050

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Honors/Awards

  • Leukemia & Lymphoma Society Scholar Award
    (2003)
  • Searle Scholar Award, the Chicago Community Trust
    (1999)
  • Eugene McDermott Scholar in Biomedical Research, UT Southwestern
    (1998)
  • Leukemia Society of America Special FellowLeukemia Society of America Special Fellow
    (1998)
  • CUSBEA Fellow, Chinese Education Ministry
    (1987)

Professional Associations/Affiliations

  • Genetic Society of America